H
Hao Sun
Researcher at Baylor College of Medicine
Publications - 14
Citations - 1186
Hao Sun is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Synaptic plasticity & Dendritic spine. The author has an hindex of 11, co-authored 14 publications receiving 1005 citations. Previous affiliations of Hao Sun include Boston Children's Hospital & University of Texas Medical Branch.
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Journal ArticleDOI
Cognitive Impairment in Pain through Amygdala-Driven Prefrontal Cortical Deactivation
TL;DR: This study shows that the amygdala contributes not only to emotional-affective but also cognitive effects of pain, which has important implications for the understanding of amygdala functions and amygdalo-cortical interactions.
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SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties
Kihoon Han,Kihoon Han,J. Lloyd Holder,J. Lloyd Holder,Christian P. Schaaf,Christian P. Schaaf,Hui Lu,Hui Lu,Hongmei Chen,Hongmei Chen,Hyojin Kang,Hyojin Kang,Hyojin Kang,Jianrong Tang,Jianrong Tang,Zhenyu Wu,Zhenyu Wu,Shuang Hao,Shuang Hao,Sau Wai Cheung,Peng Yu,Peng Yu,Hao Sun,Hao Sun,Amy M. Breman,Ankita Patel,Hui-Chen Lu,Huda Y. Zoghbi +27 more
TL;DR: This article found that incorrect gene dosage of SHANK3 (a gene linked to some human neuropsychiatric disorders, including autism spectrum disorder) is associated with behavioural abnormalities including mania, possibly because of actin regulation problems in excitatory/inhibitory synapses.
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Δ9-THC-Caused Synaptic and Memory Impairments Are Mediated through COX-2 Signaling
Rongqing Chen,Jian Zhang,Ni Fan,Zhao-Qian Teng,Yan Wu,Hongwei Yang,Ya-Ping Tang,Hao Sun,Yunping Song,Chu Chen +9 more
TL;DR: The results suggest that the applicability of medical marijuana would be broadened by concurrent inhibition of COX-2, an inducible enzyme that converts arachidonic acid to prostanoids in the brain.
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GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.
Chia Shan Wu,Hongmei Chen,Hao Sun,Jie Zhu,Chris P. Jew,James Wager-Miller,Alex Straiker,Corinne M. Spencer,Heather B. Bradshaw,Ken Mackie,Hui-Chen Lu +10 more
TL;DR: The results suggest that GPR55 plays a role in motor coordination, but does not strongly regulate CNS development, gross motor movement or several types of learned behavior.
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Sensing of Blood Pressure Increase by Transient Receptor Potential Vanilloid 1 Receptors on Baroreceptors
TL;DR: These findings provide important new information that TRPV1 is expressed along the entire baroreceptive afferent pathway and can function as mechanoreceptors to detect the increase in blood pressure and maintain the homoeostasis.