V
Vassilios Ioannidis
Researcher at Swiss Institute of Bioinformatics
Publications - 29
Citations - 3483
Vassilios Ioannidis is an academic researcher from Swiss Institute of Bioinformatics. The author has contributed to research in topics: Medicine & Interleukin 21. The author has an hindex of 15, co-authored 24 publications receiving 2773 citations. Previous affiliations of Vassilios Ioannidis include University of Basel & Ludwig Institute for Cancer Research.
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ExPASy: SIB bioinformatics resource portal.
Panu Artimo,Manohar Jonnalagedda,Konstantin Arnold,Delphine Baratin,Gábor Csárdi,Edouard de Castro,Séverine Duvaud,Volker Flegel,Arnaud Fortier,Elisabeth Gasteiger,Aurélien Grosdidier,Céline Hernandez,Vassilios Ioannidis,Dmitry Kuznetsov,Robin Liechti,Sébastien Moretti,Khaled Mostaguir,Nicole Redaschi,Grégoire Rossier,Ioannis Xenarios,Heinz Stockinger +20 more
TL;DR: The new web interface provides, in particular, visual guidance for newcomers to ExPASy, becoming an extensible and integrative portal accessing many scientific resources, databases and software tools in different areas of life sciences.
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Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development
Anita Wolfer,Talitha R. Bakker,Anne Wilson,Michael Nicolas,Vassilios Ioannidis,Dan R. Littman,Christopher B. Wilson,Werner Held,H. Robson MacDonald,Freddy Radtke +9 more
TL;DR: It is shown here that tissue-specific inactivation of the gene encoding Notch1 in immature (CD25+CD44−) T cell precursors does not affect subsequent thymocyte development, and formally excludes an essential role for NotCh1 in CD4-CD8 lineage commitment, maturation or survival.
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The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival.
TL;DR: TCF-1, upon association with β-catenin, transiently ensures the survival of immature T cells, which enables them to generate and edit T cell receptor (TCR) α chains and attempt TCR-mediated positive selection.
Journal ArticleDOI
MyHits: Improvements to an interactive resource for analyzing protein sequences
Marco Pagni,Vassilios Ioannidis,Lorenzo Cerutti,Monique Zahn-Zabal,C. Victor Jongeneel,Jörg Hau,Olivier Martin,Dmitri Kuznetsov,Laurent Falquet +8 more
TL;DR: The MyHits web site is an integrated service dedicated to the analysis of protein sequences and since its first description in 2004, both the user interface and the back end of the server were improved.
Journal ArticleDOI
Expasy, the Swiss Bioinformatics Resource Portal, as designed by its users.
Séverine Duvaud,Chiara Gabella,Frédérique Lisacek,Frédérique Lisacek,Heinz Stockinger,Vassilios Ioannidis,Christine Durinx +6 more
TL;DR: The Swiss Bioinformatics Resource Portal (expasy) as mentioned in this paper provides a portfolio of reliable and state-of-the-art resources for the storage, analysis and interpretation of biological data.