羟氨苄青霉素引起大疱性类天疱疮样疹

This article explores the emergence of Airbnb, a company whose website permits ordinary people to rent out their residences as tourist accommodation. The company was just recently established, but it has grown extremely rapidly and is now selling many millions of room nights annually. This rise is examined through the lens of disruptive innovation theory, which describes how products that lack in traditionally favoured attributes but offer alternative benefits can, over time, transform a market and capture mainstream consumers. The concepts of disruptive innovation are used to consider Airbnb's novel business model, which is built around modern internet technologies, and Airbnb's distinct appeal, which centres on cost-savings, household amenities, and the potential for more authentic local experiences. Despite Airbnb's growing popularity, many Airbnb rentals are actually illegal due to short-term rental regulations. These legality issues and their corresponding tax concerns are discussed, with an overview...

Airbnb: disruptive innovation and the rise of an informal tourism accommodation sector.

One in a while, every twenty years perhaps, a book appears that makes one see a whole area of human experience in a new light. Once pointed out, the new insights are sp obvious that one cannot understand how one could have missed them before. In the broad area of the political economy of western society, J.A. Schumpeter's Capitalism, Socialism and Democracy (1943) was one such book. So, with all its faults, was J.K. Galbraith's The Affluent Society (1957). Fred Hirsch's Social Limits to Growth (Routledge and Kegan Paul, London, 1977) is another.

Social limits to growth

OBJECTIVE To establish an indirect immunofluorescent test so as to improve the sensitivity and specificity of examination of antibodies to beta(2)-glycoprotein METHODS Full-length beta(2)GP cDNA was obtained from human hepatocellular cancer cell line HepG2 by RT-PCR and cloned into the mammalian expression vector pEGFP-C1 The recombinant plasmid pEGFP-beta(2)GP was transfected into HEp-2 cells RT-PCR, immunoblotting (IBT), confocal fluorescence microscopy, and indirect immunofluorescent test (IIF) were used to confirm the expression, localization, and antigenicity of fusion protein of green fluorescent protein (GFP) Serum specimens from 19 patients suspected as with secondary antiphospholipid syndrome (APS), 1 patient diagnosed as with primary APS, and 10 normal persons were detected with IIF-IgG-beta(2)GP1, ELISA-IgG-ACL, and ELISA-IgG-beta(2)GP I simultaneously RESULTS (1) The HEp-beta(2)GP I cells thus obtained retained their ability of expression of beta(2)GP-I-GFP for more than ten generations This beta(2)GP-I-GFP showed the antigenicity of beta(2)GP-I with a characteristic feature (2) Seven of the 20 serum specimens from APS patients showed characteristic immunofluorescent pattern No serum specimen from normal persons showed immunofluorescent staining The comparison of results of the three methods showed that the concordance between IIF-IgG-beta(2)GP I and ELISA-IgG-beta(2)GP I was the most perfect (Kappa = 0886) (3) HEp-beta(2)GP I retained the immunofluorescent property of HEp-2 cell CONCLUSION As a new kind of substrate of IIF, beta(2)GP I transfectant can be used to detect anti-beta(2)GP-I antibodies Transfeted HEp-2 cells keep the immunofluorescent property of HEp-2 cells in IFANA test and can be used as substrate for routine IFANA detection

[Expression of fusion proteins in beta(2)GP I gene-transfected HEp-2 cells and its clinical application].

http://eprints.bournemouth.ac.uk/21918/7/1-s2.0-S0261517715000679-main.pdf

Progress and prospects for event tourism research

Baade R. A. and Matheson V. A. (2004) The quest for the cup: assessing the economic impact of the World Cup, Reg. Studies 38, 343–354. Hosting the World Cup, the world’s second largest sporting event, is a potentially expensive affair. The co-hosts of the 2002 games, Japan and South Korea, spent a combined US$4 billion building new facilities or refurbishing old facilities in preparation for the event. An ex post analysis of the 1994 World Cup held in the US suggests that the economic impact of the event cannot justify this magnitude of expenditures and that host cities experienced cumulative losses of $5·5 to $9·3 billion as opposed to ex ante estimates of a $4 billion gain touted by event boosters. Potential hosts should consider with care whether the award of the World Cup is an honour or a burden.

The quest for the cup: assessing the economic impact of the World Cup.

Supporters of mega-sporting events such as the World Cup and Olympics claim that these events attract hoards of wealthy visitors and lead to lasting economic benefits for the host regions. Developing countries have become increasingly vocal in demanding a share of the economic benefits of these international games. The specialized infrastructure and operating expenses required to host these events, however, can be substantial. Independent researchers have found that boosters’ projections of the economic impact of sporting events exaggerate the true economic impact of these competitions, and these events are an even worse investment for developing countries than for industrialized nations.(This abstract was borrowed from another version of this item.)

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Mega-Sporting Events in Developing Nations: Playing the Way to Prosperity?

This paper provides an overview of the economics of sports mega-events as well as a review of the existing literature in the field. The paper describes why boosters’ ex ante estimates of the economic impact of large sporting events tend to exaggerate the net economic benefits of these events and surveys the results of a large number of ex post studies of exploring the true impact of mega-events.

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Mega-Events: The effect of the world’s biggest sporting events on local, regional, and national economies

In summer 2016, the eyes of the world will turn to Rio de Janeiro as it hosts the Games of the XXXI Olympiad, better known as the Summer Olympics. Unfortunately, the price tag of well over $10 billion for the event is adding to the already considerable strain on government budgets in Brazil. Faced with a nasty recession, cuts in public services, and rising unemployment, throngs of Brazilians have turned out to protest what is seen as wasteful spending and a misallocation of resources on the Olympics. Throw in the growing threat of the Zika virus and Brazil may end up with larger crowds of agitators protesting the government than of sports fans cheering on the athletes. But are these complaints about Olympic spending justified? The quadrennial Summer Olympic Games is one of the world’s premier sporting events, with over 10,000 athletes representing 204 countries, 300 individual events in 28 different sports, over 10 million tickets sold to spectators, and a worldwide television audience in the billions. On a somewhat smaller scale, the most recent Winter Olympic Games held in 2014 in Sochi, Russia, welcomed nearly 3,000 athletes from 88 countries to compete in 98 events in 15 disciplines while generating large revenues and massive television ratings. While most viewers tune in to watch the competition among the athletes, the battle among cities to be selected to host these events can be just as fierce. Although bidding cities have numerous reasons for wanting to host, none seems more prevalent than the desire for an economic windfall. In this paper, we explore the costs and

/pdf/going-for-the-gold-the-economics-of-the-olympics-7v4q7p1yrf.pdf

Going for the Gold: The Economics of the Olympics

/pdf/bidding-for-the-olympics-fool-s-gold-4m0udo8nw5.pdf

Victor Matheson

Papers

The quest for the cup: assessing the economic impact of the World Cup.

Mega-Sporting Events in Developing Nations: Playing the Way to Prosperity?

Mega-Events: The effect of the world’s biggest sporting events on local, regional, and national economies

Going for the Gold: The Economics of the Olympics

Bidding for the Olympics: fool's gold?