https://chemistry.mdma.ch/hiveboard/rhodium/pdf/archive/merbst/quinoline1999.pdf

Quinoline, quinazoline and acridone alkaloids

Isolation and synthesis of biologically active carbazole alkaloids

Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids

https://zenodo.org/record/1004771/files/Cushnie%20et%20al%20%282014%29%20post-peer%20reviewed%20version.pdf

Alkaloids: an overview of their antibacterial, antibiotic-enhancing and antivirulence activities.

Mosquitoes act as a vector for most of the life threatening diseases like malaria, yellow fever, dengue fever, chikungunya ferver, filariasis, encephalitis, West Nile Virus infection, etc. Under the Integrated Mosquito Management (IMM), emphasis was given on the application of alternative strategies in mosquito control. The continuous application of synthetic insecticides causes development of resistance in vector species, biological magnification of toxic substances through the food chain and adverse effects on environmental quality and non target organisms including human health. Application of active toxic agents from plant extracts as an alternative mosquito control strategy was available from ancient times. These are non-toxic, easily available at affordable prices, biodegradable and show broad-spectrum target-specific activities against different species of vector mosquitoes. In this article, the current state of knowledge on phytochemical sources and mosquitocidal activity, their mechanism of action on target population, variation of their larvicidal activity according to mosquito species, instar specificity, polarity of solvents used during extraction, nature of active ingredient and promising advances made in biological control of mosquitoes by plant derived secondary metabolites have been reviewed.

Plant extracts as potential mosquito larvicides

Antimicrobial alkaloids from Zanthoxylum tetraspermum and caudatum.

The structures of the butenolides 1 and 2, isolated from the endemic plants Hortonia floribunda, H. angustifolia, and H. ovalifolia, collected in Sri Lanka, have been elucidated by spectroscopic analysis. These compounds exhibited potent mosquito larvicidal activity against the second instar larvae of Aedes aegypti.

Two new lactones with mosquito larvicidal activity from three Hortonia species.

The stem bark of Glycosmis mauritiana contained the acridone alkaloids noracronycine and des-N- methylacronycine, and two new carbazole alkaloids, 3,3,10-trimethyl-3,7-dihydropyrano[2,3-c] carbazole (glycomaurin) and 6-methyl-4-(3′-methylbut-2′-enyl)carbazol-3-ol (glycomaurrol), whose structures were confirmed by synthesis and by cyclization to dihydroglycomaurin respectively. Glycomaurin has a ring system which has not been previously found in nature.

Vijaya Kumar

Papers

Antimicrobial alkaloids from Zanthoxylum tetraspermum and caudatum.

Two new lactones with mosquito larvicidal activity from three Hortonia species.

Glycomaurin and Glycomaurrol, New Carbazole Alkaloids From Glycosmis mauritiana (Rutaceae) Bark

Gleinene and gleinadiene, 5,7-dimethoxycoumarins from Murraya gleinei root

2,3-Dimethoxyxanthone from Hypericum mysorense☆