Vikas Anathy

TL;DR: A model in which Prxs function as peroxide dosimeters in subcellular processes that involve redox cycling, with hyperoxidation controlling structural transitions that alert cells of perturbations in peroxide homeostasis is proposed.

TL;DR: A perspective on the significance of airway epithelial cells in allergic inflammation is provided, and the relevance of the transcription factor, nuclear factor kappaB, is reviewed, and recent assays that have become available to probe the functional roles of oxidation in lung biology are discussed.

TL;DR: This study demonstrates that stimulation with Fas ligand (FasL) induces S-glutathionylation of Fas at cysteine 294 independently of nicotinamide adenine dinucleotide phosphate reduced oxidase–induced ROS, and defines a novel redox-based mechanism to propagate Fas-dependent apoptosis.

TL;DR: It is shown that IAV infection induced ER stress marker activating transcription factor-6 and endoplasmic reticulum protein 57-kD (ERp57), but not C/EBP homologous protein (CHOP).

TL;DR: It is indicated that Nox1 stimulates cell proliferation in actively cycling cells by reducing the requirement for growth factors to maintain expression of cyclin D1, whereas during cell cycle re-entry, NADPH oxidase activity is required for transcriptional activation of Fos family genes during the immediate early gene response.