V
Viky Y Suncion
Researcher at University of Miami
Publications - 18
Citations - 2719
Viky Y Suncion is an academic researcher from University of Miami. The author has contributed to research in topics: Ischemic cardiomyopathy & Stem cell. The author has an hindex of 11, co-authored 18 publications receiving 2448 citations.
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Journal ArticleDOI
Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: The POSEIDON randomized trial
Joshua M. Hare,Joel E. Fishman,Gary Gerstenblith,Darcy L. Velazquez,Juan P. Zambrano,Viky Y Suncion,Melissa Tracy,Eduard Ghersin,Peter V. Johnston,Jeffrey A. Brinker,Elayne Breton,Janice Davis-Sproul,Ivonne Hernandez Schulman,Ivonne Hernandez Schulman,John J. Byrnes,Adam Mendizabal,Maureen H. Lowery,Didier Rouy,Peter A. Altman,Cheryl Wong Po Foo,Phillip Ruiz,Alexandra Amador,José Paulo da Silva,Ian McNiece,Ian McNiece,Alan W. Heldman +25 more
TL;DR: In this early-stage study of patients with ICM, transendocardial injection of allogeneic and autologous MSCs without a placebo control were both associated with low rates of treatment-emergent SAEs, including immunologic reactions.
Journal ArticleDOI
Transendocardial Mesenchymal Stem Cells and Mononuclear Bone Marrow Cells for Ischemic Cardiomyopathy The TAC-HFT Randomized Trial
Alan W. Heldman,Darcy L. DiFede,Joel E. Fishman,Juan P. Zambrano,Barry H. Trachtenberg,Vasileios Karantalis,Muzammil Mushtaq,Adam R. Williams,Viky Y Suncion,Ian McNiece,Ian McNiece,Eduard Ghersin,Victor Soto,Gustavo Lopera,Gustavo Lopera,Roberto Miki,Howard J. Willens,Robert C. Hendel,Raul Mitrani,Pradip M. Pattany,Gary S. Feigenbaum,Behzad N. Oskouei,John J. Byrnes,Maureen H. Lowery,Julio Sierra,Mariesty V. Pujol,Cindy Delgado,Phillip Gonzalez,Jose E Rodriguez,Luiza Bagno,Didier Rouy,Peter A. Altman,Cheryl Wong Po Foo,José Paulo da Silva,Erica Anderson,Richard P Schwarz PhD,Adam Mendizabal,Joshua M. Hare +37 more
TL;DR: Transendocardial stem cell injection with MSCs or BMCs appeared to be safe for patients with chronic ischemic cardiomyopathy and LV dysfunction, and the sample size and multiple comparisons preclude a definitive statement about safety and clinical effect.
Journal ArticleDOI
Enhanced Effect of Combining Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and to Restore Cardiac Function After Myocardial Infarction
Adam R. Williams,Konstantinos E. Hatzistergos,Benjamin T. Addicott,Frederic McCall,Decio Carvalho,Viky Y Suncion,Azorides R. Morales,José Paulo da Silva,Mark A. Sussman,Alan W. Heldman,Joshua M. Hare +10 more
TL;DR: Findings illustrate important biological interactions between c-kit+ CSCs and MSCs that enhance cell-based therapeutic responses and restores diastolic and systolic function toward normal after myocardial infarct (MI).
Journal ArticleDOI
Autologous mesenchymal stem cells produce concordant improvements in regional function, tissue perfusion, and fibrotic burden when administered to patients undergoing coronary artery bypass grafting: The Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS) trial.
Vasileios Karantalis,Darcy L. DiFede,Gary Gerstenblith,Si M. Pham,James F Symes,Juan P. Zambrano,Joel E. Fishman,Pradip M. Pattany,Ian K. McNiece,John V. Conte,Steven P. Schulman,Katherine C. Wu,Ashish S. Shah,Elayne Breton,Janice Davis-Sproul,Richard P Schwarz PhD,Gary S. Feigenbaum,Muzammil Mushtaq,Viky Y Suncion,Albert C. Lardo,Ivan Borrello,Adam Mendizabal,Tomer Z. Karas,Tomer Z. Karas,John J. Byrnes,Maureen H. Lowery,Alan W. Heldman,Joshua M. Hare +27 more
TL;DR: Intramyocardial injection of autologous MSCs into akinetic yet nonrevascularized segments produces comprehensive regional functional restitution, which in turn drives improvement in global LV function.
Journal ArticleDOI
Does Transendocardial Injection of Mesenchymal Stem Cells Improve Myocardial Function Locally or Globally? An Analysis From the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis (POSEIDON) Randomized Trial
Viky Y Suncion,Eduard Ghersin,Joel E. Fishman,Juan P. Zambrano,Vasileios Karantalis,Nicole S. Mandel,Katarina H. Nelson,Gary Gerstenblith,Darcy L. Velazquez,Elayne Breton,Kranthi Sitammagari,Ivonne Hernandez Schulman,Sabrina Taldone,Adam R. Williams,Cristina Sanina,Peter V. Johnston,Jeffrey A. Brinker,Peter A. Altman,Muzammil Mushtaq,Barry H. Trachtenberg,Adam Mendizabal,Melissa Tracy,Melissa Tracy,José Paulo da Silva,Ian McNiece,Ian McNiece,Alberto C. Lardo,Richard T. George,Joshua M. Hare,Alan W. Heldman +29 more
TL;DR: Although scar size reduction was evident in all scar segments, Scar size reduction and ventricular functional responses preferentially occurred at the sites of TESI versus non-TESI sites, illustrating a dichotomy in regional responses to TESi.