The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors. While the organization of the book is similar to previous editions, major emphasis has been placed on disorders that affect multiple organ systems. Important advances in genetics, immunology, and oncology are emphasized. Many chapters of the book have been rewritten and describe major advances in internal medicine. Subjects that received only a paragraph or two of attention in previous editions are now covered in entire chapters. Among the chapters that have been extensively revised are the chapters on infections in the compromised host, on skin rashes in infections, on many of the viral infections, including cytomegalovirus and Epstein-Barr virus, on sexually transmitted diseases, on diabetes mellitus, on disorders of bone and mineral metabolism, and on lymphadenopathy and splenomegaly. The major revisions in these chapters and many

Harrison's Principles of Internal Medicine

Fruits and vegetables quality evaluation using computer vision: A review

The convolutional neural network (CNN) has been widely used in image recognition field due to its good performance. This paper proposes a facial expression recognition method based on the CNN model. Regarding the complexity of the hierarchic structure of the CNN model, the activation function is its core, because the nonlinear ability of the activation function really makes the deep neural network have authentic artificial intelligence. Among common activation functions, the ReLu function is one of the best of them, but it also has some shortcomings. Since the derivative of the ReLu function is always zero when the input value is negative, it is likely to appear as the phenomenon of neuronal necrosis. In order to solve the above problem, the influence of the activation function in the CNN model is studied in this paper. According to the design principle of the activation function in CNN model, a new piecewise activation function is proposed. Five common activation functions (i.e., sigmoid, tanh, ReLu, leaky ReLus and softplus–ReLu, plus the new activation function) have been analysed and compared in facial expression recognition tasks based on the Keras framework. The Experimental results on two public facial expression databases (i.e., JAFFE and FER2013) show that the convolutional neural network based on the improved activation function has a better performance than most-of-the-art activation functions.

The Influence of the Activation Function in a Convolution Neural Network Model of Facial Expression Recognition

Recognition and classification of paddy leaf diseases using Optimized Deep Neural network with Jaya algorithm

Forecasting yield by integrating agrarian factors and machine learning models: A survey

In this paper, we address a comprehensive study on disease recognition and classification of plant leafs using image processing methods. The traditional manual visual quality inspection cannot be defined systematically as this method is unpredictable and inconsistent. Moreover, it involves a remarkable amount of expertise in the field of plant disease diagnostics (phytopathology) in addition to the disproportionate processing times. Hence, image processing has been applied for the recognition of plant diseases. The paper has been divided into two main categories viz. detection and classification of leafs. A comprehensive discussion on the diseases detection and classification performance is presented based on analysis of previously proposed state of art techniques particularly from 1997 to 2016. Finally, discussed and classify the challenges and some prospects for future improvements in this space.

Study of digital image processing techniques for leaf disease detection and classification

A novel computer vision based neutrosophic approach for leaf disease identification and classification

Activation functions play a crucial role in discriminative capabilities of the deep neural networks. They are also one of the main reasons for revival of the neural networks. Although, recent activation functions provide solution to vanishing and exploding gradient problems, but they do not have sufficient capacity to model non-linear data. This paper proposes a novel activation function, which imparts neural networks with capability to model non-linear dependencies in data. Behavior of proposed activation function remains non-saturating even with non-linear structure. The activation function provides distinct activation behaviors to different data range segments. The paper presents two different variants of proposed function. The first, “linear sigmoidal activation” function is a fixed structure activation function with function coefficients defined at the start of model design. Whereas second, “adaptive linear sigmoidal activation” function is a trainable function which can adapt itself according to the complexity of the given data. Both of the proposed models are tested against the state of the art activation functions on benchmark datasets (CIFAR-10, MNIST, SVHN, FER-2013). The proposed activation function is able to outperforms every known activation functions in all the tests.

Linearized sigmoidal activation: A novel activation function with tractable non-linear characteristics to boost representation capability

Our country has vast potential to come up as a cardinal exporter of agricultural produce, but lack of quick quality evaluation techniques, huge losses in processing and handling after harvesting, diseased crop etc. result in a lower contribution to global market. The tomato crop is often infected by a disease, where plant's leaves get covered with spots of colors dark brown with purple border and light grey center; termed as Septoria Leaf Spot. It causes the leaves to turn yellow, but most damage occurs due to loss of leaves by infection. In this paper, tomato maturity based on color and fungal infection in the tomato leaves is determined. Initially thresholding algorithm was performed to determine the maturity of tomato. To make the system more generalized and self-adapting a shift to k-means clustering algorithm is made. Finally a comparative analysis of both the methods was done to analyze which method is more suitable in different conditions. Also an unconventional machine vision system has been suggested that scrutinizes the leaves emerging out of the soil and depending upon leaf spots, it analyzes the nature of fungus and its depth into the stem of tomato. k-means algorithm along with thresholding is used for segmentation of image and eventually identifying fungus. The fungus part that is segmented, is then studied to derive the percentage of presence.

Maturity and disease detection in tomato using computer vision

Many recent computational photography techniques play a significant role to avoid limitation of standard digital cameras to handle wide dynamic range of the real-world scenes, containing brightly and poorly illuminated areas. In many of these techniques, it is often desirable to fuse details from images captured at different exposure settings, while avoiding visual artifacts. In this paper we propose a novel technique for exposure fusion in which Weighted Least Squares (WLS) optimization framework is utilized for weight map refinement. Computationally simple texture features (i.e., detail layer extracted with the help of edge preserving filter) and color saturation measure are preferred for quickly generating weight maps to control the contribution from an input set of multiexposure images. Instead of employing intermediate High Dynamic Range (HDR) reconstruction and tone mapping steps, well-exposed fused image is generated for displaying on conventional display devices. A further advantage of the present technique is that it is well suited for multifocus image fusion. Simulation results are compared with a number of existing single resolution and multiresolution techniques to show the benefits of the proposed scheme for variety of cases.

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Vinay Kumar

Papers

Study of digital image processing techniques for leaf disease detection and classification

A novel computer vision based neutrosophic approach for leaf disease identification and classification

Linearized sigmoidal activation: A novel activation function with tractable non-linear characteristics to boost representation capability

Maturity and disease detection in tomato using computer vision

Weighted Least Squares Based Detail Enhanced Exposure Fusion