V
Vincent C. Hascall
Researcher at University of Michigan
Publications - 14
Citations - 1588
Vincent C. Hascall is an academic researcher from University of Michigan. The author has contributed to research in topics: Proteoglycan & Chondroitin sulfate. The author has an hindex of 10, co-authored 14 publications receiving 1582 citations. Previous affiliations of Vincent C. Hascall include Mount Sinai St. Luke's and Mount Sinai Roosevelt.
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Journal ArticleDOI
Isolation and characterization of proteoglycans from the swarm rat chondrosarcoma.
TL;DR: Proteoglycan monomer (D1) and aggregate (A1) preparations were isolated from 4 M guanidinium chloride extracts of the Swarm rat chondrosarcoma and contained only small proteoglycan fragments, indicating that extensive enzymatic degradation had occurred.
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Physical properties and polydispersity of proteoglycan from bovine nasal cartilage.
TL;DR: Combined rheological and centrifugal analyses suggest that the molecular weight polydispersity of proteoglycan subunit is closely approximated by a Gaussian curve with a mean of 2.5 x 106 and a standard deviation of 1.2 x 106, a consequence of the fact that the macromolecules are highly branched polymers.
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Treatment of bovine nasal cartilage proteoglycan with chondroitinases from Flavobacterium heparinum and Proteus vulgaris.
TL;DR: The results indicate that the noncovalent interactions which are essential for the aggregation of proteoglycans do not require the presence of the chondroitin sulfate portion of the macromolecules.
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Isolation and characterization of proteoglycans from chick limb bud chondrocytes grown in vitro.
TL;DR: Chick limb bud mesenchyme cells from stage 23-24 embryos were isolated and grown in culture under conditions facilitating chondrogenic development and dissociative extraction methods were used to isolate proteoglycans from Day 8 cultures.
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The effect of proteoglycans on the formation of fibrils from collagen solutions.
TL;DR: The data support the thesis that the organization of collagen fibrils in tissues may be related to amounts and kinds of proteoglycans in the tissues.