V
Vineet Kumar
Researcher at Science Applications International Corporation
Publications - 66
Citations - 1860
Vineet Kumar is an academic researcher from Science Applications International Corporation. The author has contributed to research in topics: Ionic liquid & Catalysis. The author has an hindex of 24, co-authored 66 publications receiving 1667 citations. Previous affiliations of Vineet Kumar include Johns Hopkins University & University of Delhi.
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Naturally occurring aristolactams, aristolochic acids and dioxoaporphines and their biological activities
TL;DR: Aristolactams, having a phenanthrene chromophore are a small group of compounds mainly found in the Aristolochiaceae together with the aristolochic acids and 4,5-dioxoaporphines, which are reviewed and classified on the basis of their oxygenation pattern.
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Novel chalcone derivatives as potent Nrf2 activators in mice and human lung epithelial cells.
Vineet Kumar,Sarvesh Kumar,Mohammad Hassan,Hailong Wu,Rajesh K. Thimmulappa,Amit Kumar,Sunil K. Sharma,Virinder S. Parmar,Shyam Biswal,Sanjay V. Malhotra +9 more
TL;DR: The studies showed 2-trifluoromethyl-2'-methoxychalone (2b) to be a potent activator of Nrf2, both in vitro and in mice, and showed that the activation of NRF2 by this compound is independent of reactive oxygen species or redox changes.
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Study on the potential anti-cancer activity of phosphonium and ammonium-based ionic liquids
Vineet Kumar,Sanjay V. Malhotra +1 more
TL;DR: In this paper, the anti-cancer activity and cytotoxicity of ammonium and phosphonium-based ionic liquids (ILs) have been determined for the first time via NCI's in vitro 60 human tumor cell lines.
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A profile of the in vitro anti-tumor activity of imidazolium-based ionic liquids.
Sanjay V. Malhotra,Vineet Kumar +1 more
TL;DR: The ionic liquids with alkyl substitution of C-12 chain length were found to be effective against all 60 tumor cell lines and show very low cytotoxicity in most of the cases.
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NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation
Jung Hyun Kim,Rajesh K. Thimmulappa,Vineet Kumar,Wanchang Cui,Sarvesh Kumar,Ponvijay Kombairaju,Hao Zhang,Joseph B. Margolick,William Matsui,Thomas J. MacVittie,Sanjay V. Malhotra,Shyam Biswal +11 more
TL;DR: It is determined that activation of nuclear factor erythroid-2-related factor 2 (NRF2) signaling enhances hematopoietic stem progenitor cell (HSPC) function and mitigates IR-induced myelosuppression and mortality in mice.