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Vipin Kumar

Researcher at Indian Institute of Technology Delhi

Publications -  8
Citations -  161

Vipin Kumar is an academic researcher from Indian Institute of Technology Delhi. The author has contributed to research in topics: Catalysis & Chemical glycosylation. The author has an hindex of 4, co-authored 8 publications receiving 150 citations. Previous affiliations of Vipin Kumar include University of Konstanz.

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Glycoside bond formation via acid-base catalysis.

TL;DR: Acid-base catalyzed glycosyl donor and then Glycosyl acceptor activation with phenylboron difluoride or diphenylborons fluoride permits hydrogen bond mediated intramolecular S(N)2-type glycosidation in generally high anomeric selectivity.
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Synthesis of Glycosylthiols and Reactivity Studies

TL;DR: The acid-catalyzed reaction of 1,2-anhydro-3,4,6-tri-O-benzyl-α-d-glucopyranose as glycosyl donor with bis-trimethylsilyl sulfide as acceptor affords the α-thiol, which should provide with O-glycosyl trichloroacetimidates as Glycosyl donors that have nonparticipating groups at C-2.
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Iodine catalyzed one-pot diamination of glycals with chloramine-T: a new approach to 2-amino-β-glycosylamines for applications in N-glycopeptide synthesis

TL;DR: Iodine catalyzes a facile one-pot direct diamination of glycals with chloramine-T to afford stereoselectively 2-amino-beta-glycosylamine derivatives that serve as convenient precursors for the synthesis of N-linked glycopeptides.
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A versatile strategy for the synthesis of N-linked glycoamino acids from glycals.

TL;DR: A versatile route for the synthesis of N-linked glycoamino acids from readily available glycals is reported and an illustrative synthesis of an N- linked glycopeptide 29 is also reported.

Compritrol ATO 888 based solid lipid nanoparticles of cefixime: Formulation and evaluation

TL;DR: Results showed that cefixime absorption is enhanced by using solid lipid nanoparticles formulations and the relative bioavailability of cefIXime-SLNs was found to be 1.87%.