V
Virapong Prachayasittikul
Researcher at Mahidol University
Publications - 268
Citations - 7566
Virapong Prachayasittikul is an academic researcher from Mahidol University. The author has contributed to research in topics: Quantitative structure–activity relationship & Superoxide dismutase. The author has an hindex of 43, co-authored 263 publications receiving 6251 citations.
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Journal ArticleDOI
8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications
TL;DR: Diverse bioactivities of 8HQ and newly synthesized 8HQ-based compounds are discussed together with their mechanisms of actions and structure–activity relationships.
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Bioactive Metabolites from Spilanthes acmella Murr.
Supaluk Prachayasittikul,Saowapa Suphapong,Apilak Worachartcheewan,Ratana Lawung,Somsak Ruchirawat,Virapong Prachayasittikul +5 more
TL;DR: These findings demonstrate for the first time the potential benefits of this medicinal plant as a rich source of high therapeutic value compounds for medicines, cosmetics, supplements and as a health food.
A practical overview of quantitative structure-activity relationship
Chanin Nantasenamat,Chartchalerm Isarankura-Na-Ayudhya,Thanakorn Naenna,Virapong Prachayasittikul +3 more
TL;DR: This review aims to cover the essential concepts and techniques that are relevant for performing QSAR/QSPR studies through the use of selected examples from the authors' previous work.
Journal ArticleDOI
Advances in computational methods to predict the biological activity of compounds.
TL;DR: This review presents an overview of the advances in the computational methods utilized for predicting the biological activity of compounds and a conceptual view of the quantitative structure–activity relationship paradigm and the methodological overview of commonly used machine learning algorithms.
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Synthesis, biological evaluation and molecular docking of novel chalcone-coumarin hybrids as anticancer and antimalarial agents.
Ratchanok Pingaew,Amporn Saekee,Prasit Mandi,Chanin Nantasenamat,Supaluk Prachayasittikul,Somsak Ruchirawat,Virapong Prachayasittikul +6 more
TL;DR: Molecular docking suggested that the cytotoxicity of reported hybrids could be possibly due to their dual inhibition of α- and β-tubulins at GTP and colchicine binding sites, respectively, and falcipain-2 was identified to be a plausible target site of the hybrids given their antimalarial potency.