V
Virginie Bette
Researcher at University of Cologne
Publications - 2
Citations - 92
Virginie Bette is an academic researcher from University of Cologne. The author has contributed to research in topics: Enantioselective synthesis & Tropolone. The author has an hindex of 2, co-authored 2 publications receiving 88 citations.
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Total synthesis of (-)-colchicine via a Rh-triggered cycloaddition cascade.
TL;DR: A synthesis of the antimitotic alkaloids (-)-colchicine and (-)-isocolchicines is reported, which opens an efficient enantioselective access to colchichine and structural analogues.
Journal ArticleDOI
Total Synthesis of (-)-Colchicine via a Rh-Triggered Cycloaddition Cascade
TL;DR: In this article, an enantioselective transfer-hydrogenation of an alkynone, with subsequent aromatic acylation, was reported, followed by a rh-catalyzed transformation of an alpha-diazoketone into an oxatetracyclic key intermediate.