V
Vladimir V. Zarubaev
Researcher at Pasteur Institute
Publications - 142
Citations - 1902
Vladimir V. Zarubaev is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Virus & Chemistry. The author has an hindex of 19, co-authored 110 publications receiving 1356 citations.
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Journal ArticleDOI
Influenza epidemics and acute respiratory disease activity are associated with a surge in autopsy-confirmed coronary heart disease death: results from 8 years of autopsies in 34 892 subjects
Mohammad Madjid,Mohammad Madjid,Charles C. Miller,Vladimir V. Zarubaev,Ivan G. Marinich,Oleg I. Kiselev,Yury V. Lobzin,Alexander E. Filippov,Samuel Ward Casscells,Samuel Ward Casscells +9 more
TL;DR: Influenza epidemics are associated with a rise in autopsy-confirmed coronary deaths and Influenza vaccination should be advocated for patients at high risk of developing cardiovascular events.
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Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus.
Vladimir V. Zarubaev,Efim L. Golod,Pavel Anfimov,Anna A. Shtro,Victor V. Saraev,Alexey S. Gavrilov,Alexander V. Logvinov,Oleg I. Kiselev +7 more
TL;DR: It is demonstrated that influenza viruses can be inhibited by adamantyl-azoles and thus have potential for developing antiviral agents with an alternate mechanism of action.
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Anti-viral activity of (-)- and (+)-usnic acids and their derivatives against influenza virus A(H1N1)2009.
Dmitriy N. Sokolov,Vladimir V. Zarubaev,Anna A. Shtro,Marina P. Polovinka,Olga A. Luzina,Nina I. Komarova,Nariman F. Salakhutdinov,Oleg I. Kiselev +7 more
TL;DR: In this article, the antiviral activity of usnic acid and its derivatives against the pandemic influenza virus A(H1N1)pdm09 was studied for the first time, and a total of 26 compounds representing (+) and (-) isomers of usnik acid and their derivates were tested for cytotoxicity and anti-viral activity in MDCK cells by microtetrazolium test and virus yield assay, respectively.
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Discovery of a new class of antiviral compounds: camphor imine derivatives.
A. S. Sokolova,Olga I. Yarovaya,Olga I. Yarovaya,Andrey V. Shernyukov,Yuriy V. Gatilov,Yuliya V. Razumova,Vladimir V. Zarubaev,Tatiana S. Tretiak,Andrey G. Pokrovsky,Oleg I. Kiselev,Nariman F. Salakhutdinov +10 more
TL;DR: A new class of compounds featuring a camphor moiety that exhibits potent inhibitory activity against influenza A (H1N1)pdm09 and A(H5N1), and the most potent antiviral compound is imine 2 with therapeutic index more than 500.
Journal ArticleDOI
Broad range of inhibiting action of novel camphor-based compound with anti-hemagglutinin activity against influenza viruses in vitro and in vivo
Vladimir V. Zarubaev,Angelica V. Garshinina,Tatiana S. Tretiak,V.A. Fedorova,Anna A. Shtro,A. S. Sokolova,Olga I. Yarovaya,Nariman F. Salakhutdinov +7 more
TL;DR: Anti-influenza activity of camphor derivative 1,7,7-trimethylbicyclo (camphecene) is reported, showing the compound appeared the most effective when added at the early stages of viral life cycle and in direct hemagglutinin inhibition tests camphecenes was shown to decrease the activity of HA's of influenza viruses A and B.