W. Chaowagul

TL;DR: Melioidosis may result from either acute exposure to the organism in the soil and water, or 're-activation' of an asymptomatic childhood infection (by an unidentified possibly infective seasonal cofactor).

TL;DR: Of 118 adult patients followed long-term, 27 had culture-proven relapses of melioidosis (3 relapsed twice), a relapse rate of 15% (95% confidence interval, 11-22) per year, and the median time from discharge to relapse was 21 weeks (range, 1-290).

TL;DR: Several of the new beta-lactam antibiotics are of potential value in the therapy of P. pseudomallei infections, and patients should be carefully monitored for the emergence of antibiotic-resistant strains during treatment of melioidosis.

TL;DR: Data suggest that during gram-negative sepsis, IFN-gamma production is controlled at least in part by endogenous IL-18, IL-12, and IL-15.

TL;DR: Pseudomonas pseudomallei parotitis should be considered in children from endemic areas with fever and facial swelling, because it has a good prognosis with appropriate treatment and may also prove to be a sensitive clinical indicator of the presence of melioidosis within a particular geographic area.