M
M. Kurimoto
Publications - 3
Citations - 510
M. Kurimoto is an academic researcher. The author has contributed to research in topics: Chemokine & Interleukin 12. The author has an hindex of 3, co-authored 3 publications receiving 472 citations.
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Journal ArticleDOI
Proinflammatory Effects of IL-10 During Human Endotoxemia
TL;DR: In this paper, a bolus i.v. injection of LPS (4 ng/kg) in combination with either placebo or recombinant human IL-10 was administered just before or 1 h after LPS.
Journal ArticleDOI
Elevated Plasma Concentrations of Interferon (IFN)–γ and the IFN‐γ–Inducing Cytokines Interleukin (IL)–18, IL‐12, and IL‐15 in Severe Melioidosis
F. N. Lauw,Andrew J. H. Simpson,Andrew J. H. Simpson,Jan M. Prins,M. D. Smith,M. D. Smith,M. Kurimoto,S. J. H. Van Deventer,Peter Speelman,W. Chaowagul,N J White,N J White,T. van der Poll +12 more
TL;DR: Data suggest that during gram-negative sepsis, IFN-gamma production is controlled at least in part by endogenous IL-18, IL-12, and IL-15.
Journal ArticleDOI
Interleukin-12 Induces Sustained Activation of Multiple Host Inflammatory Mediator Systems in Chimpanzees
F. N. Lauw,Pascale E. P. Dekkers,A. A. Te Velde,Peter Speelman,M. Levi,M. Kurimoto,C. E. Hack,S. J. H. Van Deventer,T. van der Poll +8 more
TL;DR: In this paper, the effects of recombinant human interleukin (IL)-12 on host inflammatory mediator systems were found to be only after 8-24 h, remained detectable until the end of the 48-h observation period, and occurred in the absence of detectable TNF and IL-1beta.