W
W. G. Lock
Researcher at Newcastle University
Publications - 2
Citations - 405
W. G. Lock is an academic researcher from Newcastle University. The author has contributed to research in topics: CDC37 & Cell cycle checkpoint. The author has an hindex of 2, co-authored 2 publications receiving 388 citations. Previous affiliations of W. G. Lock include University of Cambridge.
Papers
More filters
Journal ArticleDOI
Genome-wide survey of protein kinases required for cell cycle progression.
Mónica Bettencourt-Dias,Régis Giet,Régis Giet,Rita Sinka,A. Mazumdar,W. G. Lock,Francois Balloux,P. J. Zafiropoulos,Shinji Yamaguchi,S. Winter,Richard W. Carthew,Mark E. Cooper,D. Jones,Lisa M. Frenz,David M. Glover +14 more
TL;DR: The complement of Drosophila protein kinases (kinome) is tested for cell cycle functions after gene silencing by RNA-mediated interference, revealing the inter-digitation of systems that monitor cellular physiology, cell size, cellular stress and signalling processes with the basic cell cycle regulatory machinery.
Journal ArticleDOI
Evidence that prostate gonadotropin-releasing hormone receptors mediate an anti-tumourigenic response to analogue therapy in hormone refractory prostate cancer
TL;DR: Data support the notion of a functional interaction between GnRHa and the GnRHR, which results in an anti‐tumourigenic effect on prostate cancer cells.