W
W. G. V. Quint
Researcher at GlaxoSmithKline
Publications - 82
Citations - 3787
W. G. V. Quint is an academic researcher from GlaxoSmithKline. The author has contributed to research in topics: Population & Polymerase chain reaction. The author has an hindex of 32, co-authored 80 publications receiving 3602 citations.
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Journal ArticleDOI
Development and Clinical Evaluation of a Highly Sensitive PCR-Reverse Hybridization Line Probe Assay for Detection and Identification of Anogenital Human Papillomavirus
Berhard Kleter,L. van Doorn,Lianne Schrauwen,Anco Molijn,S. Sastrowijoto,J. Ter Schegget,Jan H.N. Lindeman,B. ter Harmsel,Matthé P.M. Burger,W. G. V. Quint +9 more
TL;DR: The SPF LiPA method allows extremely sensitive detection of HPV DNA as well as reliable identification of HPV genotypes in both cervical smears and paraffin-embedded materials.
Journal ArticleDOI
Comparison of phage typing and DNA fingerprinting by polymerase chain reaction for discrimination of methicillin-resistant Staphylococcus aureus strains.
A. van Belkum,R. Bax,Paul G. H. Peerbooms,Wilhelmus Hubertus Francisus Goessens,N. Van Leeuwen,W. G. V. Quint +5 more
TL;DR: A typing procedure for methicillin-resistant Staphylococcus aureus (MRSA) based on the polymerase chain reaction (PCR) amplification of both mecA sequences and variable DNA sequences as present in the prokaryotic genome has been developed.
Journal ArticleDOI
Detection of Mycoplasma pneumoniae by Two Polymerase Chain Reactions and Role of M. pneumoniae in Acute Respiratory Tract Infections in Pediatric Patients
TL;DR: Provided a specific internal control is used, sample preparation by freeze-boiling combined with PCR for the PI gene and amplicon detection by visual inspection of the electrophoresis gel can be recommended, although maximal results are obtained after hybridization.
Journal ArticleDOI
Importance of Helicobacter pylori cagA and vacA status for the efficacy of antibiotic treatment.
L.J. van Doorn,Peter M. Schneeberger,Nathalie Nouhan,A. P. Plaisier,W. G. V. Quint,W.A. de Boer +5 more
TL;DR: The strong association between the cagA and vacA status and peptic ulcer disease was confirmed and cure rates seem to be higher for patients with H pylori strains, which is consistent with the higher cure rate observed among ulcer patients compared with functional dyspepsia patients.
Journal ArticleDOI
Nosocomial colonization and infection with multiresistant Acinetobacter baumannii : outbreak delineation using DNA macrorestriction analysis and PCR-fingerprinting
Marc Struelens,E. Carlier,Nicole Maes,Elisabeth Schoutens Serruys,W. G. V. Quint,A. van Belkum +5 more
TL;DR: Wider use of sensitive genotypic methods like DNA macrorestriction analysis and PCR-mediated fingerprinting for typing nosocomial pathogens should improve the detection of micro-epidemics amenable to early control.