H
Hubert G. M. Niesters
Researcher at University Medical Center Groningen
Publications - 341
Citations - 17708
Hubert G. M. Niesters is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Hepatitis B & Hepatitis B virus. The author has an hindex of 70, co-authored 324 publications receiving 16571 citations. Previous affiliations of Hubert G. M. Niesters include Erasmus University Rotterdam & University of Groningen.
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Journal ArticleDOI
Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial
Harry L.A. Janssen,Monika van Zonneveld,Hakan Senturk,Stefan Zeuzem,Ulus Salih Akarca,Yilmaz Cakaloglu,Christopher Simon,Thomas M K So,Guido Gerken,Robert A. de Man,Hubert G. M. Niesters,Pieter E. Zondervan,Bettina E. Hansen,Solko W. Schalm +13 more
TL;DR: Treatment with pegylated interferon alfa-2b is effective for HBeAg-positive chronic hepatitis B and combination with lamivudine in the regimen used is not superior to monotherapy.
Journal ArticleDOI
Human bocavirus and acute wheezing in children.
Tobias Allander,Tobias Allander,Tuomas Jartti,Shawon Gupta,Shawon Gupta,Hubert G. M. Niesters,Pasi Lehtinen,Riikka üsterback,Tytti Vuorinen,Matti Waris,Annelie Bjerkner,Annelie Bjerkner,Annika Tiveljung-Lindell,Annika Tiveljung-Lindell,Bernadette G. van den Hoogen,Timo Hyypiä,Olli Ruuskanen +16 more
TL;DR: Results suggest a model for bocavirus infection in which high viral loads are potentially associated with respiratory symptoms and low viral loads indicate asymptomatic shedding, and quantitative polymerase chain reaction analysis may be important for additional studies of human bocvirus.
Journal ArticleDOI
Genus and species- specific identification of mycoplasmas by 16s rrna amplification
F.J.M. van Kuppeveld,J. T. M. Van Der Logt,A.F. Angulo,M.J. van Zoest,W.G.V. Quint,Hubert G. M. Niesters,Jochem M. D. Galama,Willem J. G. Melchers +7 more
TL;DR: Systematic computer alignment of mycoplasmal 16S rRNA sequences allowed the identification of variable regions with both genus- and species-specific sequences, and Mycoplasma collis proved to be species specific in the polymerase chain reaction.
Journal ArticleDOI
Prevention of Epstein-Barr virus-lymphoproliferative disease by molecular monitoring and preemptive rituximab in high-risk patients after allogeneic stem cell transplantation.
Joost W. J. van Esser,Hubert G. M. Niesters,Bronno van der Holt,Ellen Meijer,Albert D. M. E. Osterhaus,Jan W. Gratama,Leo F. Verdonck,Bob Löwenberg,Jan J. Cornelissen +8 more
TL;DR: Frequent quantitative monitoring of EBV reactivation and preemptive therapy by rituximab improves outcome in patients at high risk ofEBV-LPD.
Journal ArticleDOI
Epstein-Barr virus (EBV) reactivation is a frequent event after allogeneic stem cell transplantation (SCT) and quantitatively predicts EBV-lymphoproliferative disease following T-cell--depleted SCT
Joost W. J. van Esser,Bronno van der Holt,Ellen Meijer,Hubert G. M. Niesters,Rudolf Trenschel,Steven F. T. Thijsen,Anton M. van Loon,Francesco Frassoni,Andrea Bacigalupo,Ulrich W. Schaefer,Albert D. M. E. Osterhaus,Jan W. Gratama,Bob Löwenberg,Leo F. Verdonck,Jan J. Cornelissen +14 more
TL;DR: It is concluded that EBV reactivation occurs frequently after TCD and unmanipulated allo-SCT, especially in recipients of grafts with high CD34(+) cell counts, and EBV load quantitatively predicted EBV-LPD in recipient of a TCD graft.