scispace - formally typeset
W

W.S. Fred Wong

Researcher at National University of Singapore

Publications -  91
Citations -  4801

W.S. Fred Wong is an academic researcher from National University of Singapore. The author has contributed to research in topics: Bronchoalveolar lavage & Andrographolide. The author has an hindex of 33, co-authored 81 publications receiving 4050 citations. Previous affiliations of W.S. Fred Wong include University Health System.

Papers
More filters
Journal ArticleDOI

Antisense oligonucleotides: from design to therapeutic application.

TL;DR: The present review discusses various theoretical approaches to rational design of AsO, chemical modifications of ASO, ASO delivery systems and ASO‐related toxicology, and surveys ASO drugs in various current clinical studies.
Journal ArticleDOI

Artemisinins: Pharmacological actions beyond anti-malarial

TL;DR: Artemisinins have demonstrated cytotoxic effects against a variety of cancer cells by inducing cell cycle arrest, promoting apoptosis, preventing angiogenesis, and abrogating cancer invasion and metastasis, and it is likely that artemisinin drugs will become a major armamentarium combating a number of human diseases beyond malaria.
Journal ArticleDOI

Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model.

TL;DR: Histological studies show that U0126 dramatically inhibited OVA-induced lung tissue eosinophilia, airway mucus production, and expression of VCAM-1 in lung tissues, and implicate that inhibition of ERK signaling pathway may have therapeutic potential for the treatment of allergic airway inflammation.
Journal ArticleDOI

Vitamin E therapy beyond cancer: Tocopherol versus tocotrienol

TL;DR: An update on vitamin E therapeutic potentials, protective effects and modes of action beyond cancer, with comparison of tocopherols against tocotrienols.
Journal ArticleDOI

Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer.

TL;DR: An attempt is made to evaluate the phytochemical properties of the fruit extract of Andrographis paniculata which has potential in finding its application in medicine and herbal formulations.