Wahab A. Khan

TL;DR: A 1-year-old male child from Guyana with obesity, postaxial polydactyly on his right foot, hypotonia, ophthalmologic abnormalities, and developmental delay together indicated a clinical diagnosis of Bardet–Biedl syndrome, and the identification of this shared haplotype in the parents suggests that this pathogenic aberration may be a BBS founder mutation in the Guyanese population.

TL;DR: A hybrid algorithm that uses Gradient Vector Flow active contours, Discrete Curve Evolution based skeleton pruning and morphological thinning to provide a reliable centerline that is robust to shape variations of the chromosomes is proposed.

TL;DR: A prototype software system with sufficient capacity and speed to estimate radiation exposures in a mass casualty event by counting dicentric chromosomes (DCs) in metaphase cells from many individuals is presented.

TL;DR: A hybrid algorithm is proposed that utilizes Gradient Vector Flow active contours, Discrete Curve Evolution based skeleton pruning and morphological thinning to provide a robust and accurate centerline of the chromosome, which is then used for the measurement of the FISH probe signals.

TL;DR: There are localized differences in compaction of homologs during mitotic metaphase and that these differences may arise during or preceding metaphase chromosome compaction, providing evidence that DA is non-random and reproducible.