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Wang Gary T
Researcher at Walter and Eliza Hall Institute of Medical Research
Publications - 15
Citations - 274
Wang Gary T is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Neuraminidase & Cancer. The author has an hindex of 5, co-authored 15 publications receiving 274 citations.
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Patent
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
Milan Bruncko,Hong Ding,George A. Doherty,Steven W. Elmore,Lisa A. Hasvold,Laura Hexamer,Kunzer Aaron R,Xiaohong Song,Andrew J. Souers,Gerard M. Sullivan,Zhi-Fu Tao,Wang Gary T,Le Wang,Xilu Wang,Michael D. Wendt,Robert A. Mantei,Todd M. Hansen +16 more
TL;DR: In this paper, compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-APOPotic BCL-2 protein.
Patent
Sulfonamide derivatives as bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
Chang H. Park,Milan Bruncko,Hong Ding,George Doherty,Steven W. Elmore,Hasvold Lisa,Hexamer Laura,Kunzer Aaron R,Robert A. Mantei,Mcclellan William J,Cheol-Min Park,Andrew M. Petros,Xiaohong Song,Andrew J. Souers,Gerard M. Sullivan,Zhi-Fu Tao,Wang Gary T,Le Wang,Wang Xilu,Wendt Michael D,Todd M. Hansen +20 more
TL;DR: In this paper, compounds (I) which inhibit the activity of anti-apoptotic Bc1-2 or Bc 1 xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti apoptotic bc 1-2 protein.
Patent
Substituted phenyl farnesyltransferase inhibitors
Weibo Wang,Michael L. Curtin,Stephen A. Fakhoury,Stephen L. Gwaltney,Hasvold Lisa,Charles W. Hutchins,Qui Li,Nan-Horng Lin,Nelson Lissa T,Stephen J. O'connor,Hing L. Sham,Gerald M. Sullivan,Wang Gary T,Wang Xilu +13 more
TL;DR: In this paper, a list of compounds of formula (I) or pharmaceutically acceptable salts thereof, which inhibit farnesyltransferase, and methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treatment using the compounds are disclosed.
Patent
Pyrrolidines as inhibitors of neuraminidases
Clarence J. Maring,Yu-Gui Gu,Chen Hui-Ju,Yuanwei Chen,David A. Degoey,Flosi William J,Giranda Vincent L,David J. Grampovnik,Kati Warren M,Dale J. Kempf,Larry L. Klein,Krueger Allan C,Zhen Lin,Darold L. Madigan,Mcdaniel Keith F,Steven W. Muchmore,Hing L. Sham,Kent D. Stewart,Stoll Vincent S,Minghua Sun,Wang Gary T,Sheldon Wang,Yibo Xu,Yeung Ming C,Zhao Chen,April Kennedy +25 more
TL;DR: In this article, compounds of formula (I) which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidease, are discussed.
Patent
Imidazopyridines as a novel scaffold for multi-targeted kinase inhibition
Nwe Y. Bamaung,Richard F. Clark,Scott A. Erickson,Steve D. Fidanze,Megumi Kawai,Robert A. Mantei,George S. Sheppard,Bryan K. Sorenson,Wang Gary T +8 more
TL;DR: In this paper, a list of compounds that inhibit protein kinases, compositions containing the compounds, and methods of treating diseases using the compounds are disclosed, along with their compositions and methods.