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Wataru Ando
Researcher at Osaka University
Publications - 95
Citations - 1987
Wataru Ando is an academic researcher from Osaka University. The author has contributed to research in topics: Medicine & Mesenchymal stem cell. The author has an hindex of 23, co-authored 79 publications receiving 1585 citations. Previous affiliations of Wataru Ando include University of Calgary.
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Cartilage repair using an in vitro generated scaffold-free tissue-engineered construct derived from porcine synovial mesenchymal stem cells
Wataru Ando,Kosuke Tateishi,David A. Hart,Daisuke Katakai,Yoshinari Tanaka,Ken Nakata,Jun Hashimoto,Hiromichi Fujie,Konsei Shino,Hideki Yoshikawa,Norimasa Nakamura +10 more
TL;DR: Implantation of a TEC into chondral defects initiated repair with a chondrogenic-like tissue, as well as secure biological integration to the adjacent cartilage, which revealed mechanical properties similar to those of normal porcine cartilage in static compression and friction tests.
Journal ArticleDOI
The influence of skeletal maturity on allogenic synovial mesenchymal stem cell-based repair of cartilage in a large animal model.
Kazunori Shimomura,Wataru Ando,Kosuke Tateishi,Ryosuke Nansai,Hiromichi Fujie,David A. Hart,Hideyuki Kohda,Keisuke Kita,Takashi Kanamoto,Tatsuo Mae,Ken Nakata,Konsei Shino,Hideki Yoshikawa,Norimasa Nakamura,Norimasa Nakamura +14 more
TL;DR: The results of the present study suggest the feasibility of allogenic MSC-based cartilage repair over generations and may validate the use of immature porcine model as clinically relevant to test the viability of synovial M SC-based therapies in chondral lesions.
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In vitro generation of a scaffold-free tissue-engineered construct (TEC) derived from human synovial mesenchymal stem cells: biological and mechanical properties and further chondrogenic potential.
Wataru Ando,Kosuke Tateishi,Daisuke Katakai,David A. Hart,Chikahisa Higuchi,Ken Nakata,Jun Hashimoto,Hiromichi Fujie,Konsei Shino,Hideki Yoshikawa,Norimasa Nakamura +10 more
TL;DR: The basic TEC generates with human synovial mesenchymal stem cells possesses sufficiently self-supporting mechanical properties in spite of not containing artificial scaffolding and may be a promising method to promote cartilage repair for future clinical application.
Journal ArticleDOI
Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes.
Makoto Hirao,Jun Hashimoto,Naomi Yamasaki,Wataru Ando,Hideki Tsuboi,Akira Myoui,Hideki Yoshikawa +6 more
TL;DR: It is suggested that a low oxygen tension promotes osteoblastic differentiation and subsequent transformation to osteocytes in mice cultured under normoxic or hypoxic conditions.
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Comparison of human serum with fetal bovine serum for expansion and differentiation of human synovial MSC: potential feasibility for clinical applications.
Kosuke Tateishi,Wataru Ando,Chikahisa Higuchi,David A. Hart,Jun Hashimoto,Ken Nakata,Hideki Yoshikawa,Norimasa Nakamura +7 more
TL;DR: Results of this study indicate that HS is superior for the culture of human MSCs compared with FBS in terms of cellular expandability, without losing chondrogenic or osteogenic differentiation capacity.