W
Wayne L. Smith
Researcher at University of California, Davis
Publications - 40
Citations - 1960
Wayne L. Smith is an academic researcher from University of California, Davis. The author has contributed to research in topics: Mastitis & Paratuberculosis. The author has an hindex of 19, co-authored 40 publications receiving 1869 citations. Previous affiliations of Wayne L. Smith include University of California, Irvine.
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Journal ArticleDOI
Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils.
Michael E. Selsted,Michael J. Novotny,Wendy L. Morris,Yi-Quan Tang,Wayne L. Smith,James S Cullor +5 more
TL;DR: A potent and structurally novel antimicrobial peptide was purified from the cytoplasmic granules of bovine neutrophils and the mole percent of tryptophan in indolicidin is the highest observed among known protein sequences.
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Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
Michael E. Selsted,Yi-Quan Tang,Wendy L. Morris,Patti A. McGuire,Michael J. Novotny,Wayne L. Smith,Agnes Henschen,James S Cullor +7 more
TL;DR: A new family of cysteine-rich antimicrobial peptides from bovine neutrophils was identified and characterized in this paper, and the peptides are characterized by a highly cationic 38-42-residue chain which includes 6 invariantly spaced cysteines which form three disulfides.
Journal ArticleDOI
Quantitation of bovine cytokine mRNA in milk cells of healthy cattle by real-time TaqMan® polymerase chain reaction
Christian M. Leutenegger,Ahmed M Alluwaimi,Ahmed M Alluwaimi,Wayne L. Smith,Lynn Perani,James S Cullor +5 more
TL;DR: A novel methodology to quantitate bovine cytokines and growth factors contributing to immunity against bacterial infections of the mammary gland in cattle by decreasing the numbers of working steps shortened the time for analysis and increased accuracy.
Journal ArticleDOI
Human lysozyme expressed in the mammary gland of transgenic dairy goats can inhibit the growth of bacteria that cause mastitis and the cold-spoilage of milk.
TL;DR: Transgenic goats that expressed human lysozyme in their milk at 68% of the levels found in human milk had a bacteriostatic effect on both in vitro and in vivo growth of several microorganisms important to the dairy industry.
Journal ArticleDOI
The cytokine markers in Staphylococcus aureus mastitis of bovine mammary gland.
A. M. Alluwaimi,Christian M. Leutenegger,Thomas B Farver,Paul V. Rossitto,Wayne L. Smith,James S Cullor +5 more
TL;DR: The significant elevations of the IL-12 and TNF-alpha transcriptional level most likely indicate their important role in regulation of the immune responses of bovine mammary gland in S. aureus infection.