Wayne W. Wakeland

TL;DR: Knowing sharing in organizations, especially the impact of sharing freely versus not sharing, was studied using game theoretic analysis and a Netlogo agent-based simulation model, finding that agents who share acquire more knowledge than hoarders.

TL;DR: SOURCE (Simulation of Opioid Use, Response, Consequences, and Effects), an operationally detailed national-level model of the opioid crisis, is presented, intended to enhance understanding of the crisis and guide policy decisions.

TL;DR: As prescribing continuity increased, likelihood of filling risky opioid prescriptions and overdose hospitalization decreased, and the association between opioid-prescribing continuity, risky prescribing patterns, and overdose risk was understood.

TL;DR: It may be difficult to limit negative outcomes associated with pharmaceutical opioids without adversely affecting chronic pain patients' access to pharmaceutical treatment, and a combination of metrics and value judgments will be needed to properly evaluate mitigation strategies.

TL;DR: The in silico ICP model with session-specific parameters accurately reproduced observed ICP response to changes in head-of-bed and respiration rate and demonstrated modest success at predicting future ICP within a session and to a lesser extent between sessions.