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Wei-jie Guan

Researcher at Guangzhou Medical University

Publications -  151
Citations -  34642

Wei-jie Guan is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Bronchiectasis & Medicine. The author has an hindex of 27, co-authored 126 publications receiving 24975 citations.

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Journal ArticleDOI

Characterization of lung function impairment in adults with bronchiectasis.

TL;DR: Significant lung function impairment should raise alert of chest HRCT abnormality and sputum culture positive for Pseudomonas aeruginosa, in patients with predominantly mild to moderate steady-state bronchiectasis.
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Validation of human small airway measurements using endobronchial optical coherence tomography

TL;DR: EB-OCT, a minimally invasive imaging modality with high-resolution, is useful and clinically practical for assessing proximal and distal airways of human compared with CT and histology.
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Host immunological response and factors associated with clinical outcome in patients with the novel influenza A H7N9 infection.

TL;DR: It is demonstrated that high viral load, and the resulting intense inflammatory responses, played an important role in H7N9 pathogenesis and clinical management should be on preventing the intense cytokine response by early diagnosis and effective antiviral treatment.
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Macrolide Therapy in Adults and Children with Non-Cystic Fibrosis Bronchiectasis: A Systematic Review and Meta-Analysis

TL;DR: Macrolide maintenance therapy, both in adults and children, was effective and safe in reducing bronchiectasis exacerbations, but not the admissions for exacerbations.