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Wei-jie Guan
Researcher at Guangzhou Medical University
Publications - 151
Citations - 34642
Wei-jie Guan is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Bronchiectasis & Medicine. The author has an hindex of 27, co-authored 126 publications receiving 24975 citations.
Papers
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Journal ArticleDOI
Clinical characteristics of COVID-19 infection in chronic obstructive pulmonary disease: A multicenter, retrospective, observational study
Fan Wu,Yumin Zhou,Zhongfang Wang,Min Xie,Zhe Shi,Zhiqiang Tang,Xiaohe Li,Xiaochen Li,Chunliang Lei,Yimin Li,Zhengyi Ni,Yu Hu,Xiaoqing Liu,Wenguang Yin,Linling Cheng,Feng Ye,Jieqi Peng,Lingmei Huang,Jia Tian,Lingjuan Zhang,Xiaoneng Mo,Ying Zhang,Ke Hu,Yongliang Jiang,Wei-jie Guan,Jie Xiang,Yingxia Liu,Yi-xiang Peng,Li Wei,Ya-hua Hu,Peng Peng,Jian-ming Wang,Ji-yang Liu,Wei Huang,Ruchong Chen,Jianping Zhao,Shiyue Li,Nuofu Zhang,Jincun Zhao,Nanshan Zhong,Pixin Ran +40 more
TL;DR: Patients with COPD who developed COVID-19 showed a higher risk of admission to the intensive care unit, mechanical ventilation, or death and a significantly higher proportion of increased activated partial thromboplastin time.
Journal ArticleDOI
Characterization of lung function impairment in adults with bronchiectasis.
Wei-jie Guan,Yong-hua Gao,Gang Xu,Zhi-ya Lin,Yan Tang,Hui-min Li,Zhi-min Lin,Jinping Zheng,Rongchang Chen,Nanshan Zhong +9 more
TL;DR: Significant lung function impairment should raise alert of chest HRCT abnormality and sputum culture positive for Pseudomonas aeruginosa, in patients with predominantly mild to moderate steady-state bronchiectasis.
Journal ArticleDOI
Validation of human small airway measurements using endobronchial optical coherence tomography
Yu Chen,Ming Ding,Wei-jie Guan,Wei Wang,Weizhan Luo,Chang-Hao Zhong,Mei Jiang,Ju-Hong Jiang,Yingying Gu,Shiyue Li,Nanshan Zhong +10 more
TL;DR: EB-OCT, a minimally invasive imaging modality with high-resolution, is useful and clinically practical for assessing proximal and distal airways of human compared with CT and histology.
Journal ArticleDOI
Host immunological response and factors associated with clinical outcome in patients with the novel influenza A H7N9 infection.
TL;DR: It is demonstrated that high viral load, and the resulting intense inflammatory responses, played an important role in H7N9 pathogenesis and clinical management should be on preventing the intense cytokine response by early diagnosis and effective antiviral treatment.
Journal ArticleDOI
Macrolide Therapy in Adults and Children with Non-Cystic Fibrosis Bronchiectasis: A Systematic Review and Meta-Analysis
Yong-hua Gao,Wei-jie Guan,Gang Xu,Yan Tang,Yang Gao,Zhi-ya Lin,Zhi-min Lin,Nanshan Zhong,Rongchang Chen +8 more
TL;DR: Macrolide maintenance therapy, both in adults and children, was effective and safe in reducing bronchiectasis exacerbations, but not the admissions for exacerbations.