W
Wei Yang
Researcher at University of Texas at Austin
Publications - 13
Citations - 1650
Wei Yang is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Supersaturation & Dissolution testing. The author has an hindex of 11, co-authored 12 publications receiving 1506 citations. Previous affiliations of Wei Yang include Memorial University of Newfoundland.
Papers
More filters
Journal ArticleDOI
Inhaled nanoparticles—A current review
TL;DR: The potential application of pulmonary drug delivery of nanoparticles to the lungs, specifically in context of published results reported on nanomaterials in environmental epidemiology and toxicology is reviewed in this paper.
Journal ArticleDOI
Amorphous Compositions Using Concentration Enhancing Polymers for Improved Bioavailability of Itraconazole
TL;DR: Amorphous compositions of ITZ and enteric concentration enhancing polymers provided improved bioavailability due to enhanced intestinal targeting and increased durations of supersaturation, and the utility of CAP to maintain supersaturated concentrations, in vivo was suggested.
Journal ArticleDOI
Hot-Melt Extrusion for Enhanced Delivery of Drug Particles
TL;DR: It appears that rapid precipitation of ITZ occurs upon entrance into the more neutral pH environment of the small intestine resulting in a brief opportunity for absorption.
Journal ArticleDOI
Enhanced in vivo absorption of itraconazole via stabilization of supersaturation following acidic-to-neutral pH transition.
TL;DR: In this article, different polymeric stabilizers with either immediate release (IR) or enteric release (EUDRAGIT® L 100-55, HP-55S) properties were evaluated to determine the chemical and physical attributes of the stabilizers that promote supersaturation of ITZ in neutral media.
Journal ArticleDOI
Targeted Intestinal Delivery of Supersaturated Itraconazole for Improved Oral Absorption
TL;DR: The results of this study strongly suggest that substantial improvements in oral antifungal therapy with ITZ can be achieved via intestinal targeting and polymeric stabilization of supersaturation.