J
James W. McGinity
Researcher at University of Texas at Austin
Publications - 215
Citations - 12822
James W. McGinity is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Dosage form & Triethyl citrate. The author has an hindex of 62, co-authored 215 publications receiving 12131 citations. Previous affiliations of James W. McGinity include University of Texas System.
Papers
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Journal ArticleDOI
Preparation of microspheres by the solvent evaporation technique
TL;DR: The microencapsulation process in which the removal of the hydrophobic polymer solvent is achieved by evaporation has been widely reported in recent years for the preparation of microspheres and microcapsules based on biodegradable polymers and copolymers of hydroxy acids.
Journal ArticleDOI
Pharmaceutical Applications of Hot-Melt Extrusion: Part I
Michael M. Crowley,Feng Zhang,Michael A. Repka,Sridhar Thumma,Sampada B. Upadhye,Sunil Kumar Battu,James W. McGinity,Charles R. Martin +7 more
TL;DR: The pharmaceutical applications of hot-melt extrusion, including equipment, principles of operation, and process technology, are reviewed and the physicochemical properties of the resultant dosage forms are described.
Journal ArticleDOI
Solvent selection in the preparation of poly(dl-lactide) microspheres prepared by the solvent evaporation method
TL;DR: In this article, the authors used solvent evaporation to obtain poly( dl -lactide) microspheres containing quinidine or quinedinidine sulfate.
Journal ArticleDOI
Physicochemical properties and mechanism of drug release from ethyl cellulose matrix tablets prepared by direct compression and hot-melt extrusion.
Michael M. Crowley,Britta Schroeder,Anke Fredersdorf,Sakae Obara,Mark Talarico,Shawn A. Kucera,James W. McGinity +6 more
TL;DR: The Higuchi diffusion model, Percolation Theory and Polymer Free Volume Theory were applied to the dissolution data to explain the release properties of drug from the matrix systems and the release rate was shown to be dependent on the ethyl cellulose particle size, compaction force and extrusion temperature.
Patent
Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof
TL;DR: In this article, a hot-melt extruded film is used for the treatment of wounds. But it does not contain a conventional plasticizer or a material which is generally recognized in the art as a plasticizer for extruded films.