J
Jason T. McConville
Researcher at University of Texas at Austin
Publications - 44
Citations - 2083
Jason T. McConville is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Dissolution testing & Dissolution. The author has an hindex of 25, co-authored 44 publications receiving 1931 citations. Previous affiliations of Jason T. McConville include Strathclyde Institute of Pharmacy and Biomedical Sciences & University of Texas System.
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Journal ArticleDOI
Manufacture and characterization of mucoadhesive buccal films.
TL;DR: This review will consider the literature that describes the manufacture and characterization of mucoadhesive buccal films and hot-melt extrusion has been explored as an alternative manufacturing process and has yielded promising results.
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Hot-Melt Extrusion for Enhanced Delivery of Drug Particles
TL;DR: It appears that rapid precipitation of ITZ occurs upon entrance into the more neutral pH environment of the small intestine resulting in a brief opportunity for absorption.
Journal ArticleDOI
Development of a standardized dissolution test method for inhaled pharmaceutical formulations
Yoen-Ju Son,Jason T. McConville +1 more
TL;DR: This study demonstrated that the developed method was reproducible and may be used to evaluate the dissolution properties of pharmaceutical inhalation products following their aerodynamic particle classification.
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High bioavailability from nebulized itraconazole nanoparticle dispersions with biocompatible stabilizers.
Wei Yang,Jasmine M. Tam,Dave A. Miller,Jiping Zhou,Jason T. McConville,Keith P. Johnston,Robert O. Williams +6 more
TL;DR: Bioavailability may be enhanced, by decreasing the particle size to accelerate dissolution and increasing permeation with (1) an amorphous morphology to raise the drug solubility, and (2) permeability enhancers.
Journal ArticleDOI
Effect of Stabilizer on the Maximum Degree and Extent of Supersaturation and Oral Absorption of Tacrolimus Made By Ultra-Rapid Freezing
Kirk Overhoff,Jason T. McConville,Wei Yang,Keith P. Johnston,Jay I. Peters,Robert O. Williams +5 more
TL;DR: The nanostructured powders containing various stabilizing polymers formed by the URF process offer enhanced supersaturation characteristics leading to increased oral absorption of TAC.