W
Weichang Zhou
Researcher at Genzyme
Publications - 4
Citations - 400
Weichang Zhou is an academic researcher from Genzyme. The author has contributed to research in topics: Chinese hamster ovary cell & Virus. The author has an hindex of 3, co-authored 4 publications receiving 370 citations.
Papers
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Journal ArticleDOI
Integrated continuous production of recombinant therapeutic proteins
Veena Warikoo,Rahul Godawat,Kevin Brower,Sujit Jain,Daniel Cummings,Elizabeth Simons,Johnson Timothy,Jason Walther,Marcella Yu,Benjamin Wright,Jean McLarty,Kenneth P. Karey,Chris Hwang,Weichang Zhou,Frank Riske,Konstantin Konstantinov +15 more
TL;DR: The first successful demonstration of the integration of a perfusion bioreactor and a four‐column periodic counter‐current chromatography system for the continuous capture of candidate protein therapeutics is reported, demonstrating the potential of integrated continuous bioprocessing as a universal platform for the manufacture of various kinds of therapeutic proteins.
Journal ArticleDOI
Identification and quantitation of Vesivirus 2117 particles in bioreactor fluids from infected Chinese hamster ovary cell cultures.
Yongchang Qiu,Nathan Jones,Michelle Busch,Peng Pan,Jesse Keegan,Weichang Zhou,Mark Plavsic,Michael L. Hayes,John M. McPherson,Tim Edmunds,Kate Zhang,Robert J. Mattaliano +11 more
TL;DR: The identification and quantitation of Vesivirus 2117 particles in bioreactor fluid from infected Chinese hamster ovary cell cultures by global protein sequencing using mass spectrometry in combination with multi‐dimensional liquid‐chromatography is reported.
Patent
Seed train processes and uses thereof
TL;DR: In this article, the seed train processes and methods of producing a recombinant protein that include the use of these seed-train processes are described and discussed. But they do not discuss the use for recombinant proteins.
Patent
Method of cultivation in system of inoculating fermentors (embodiments)
TL;DR: In this article, a method of producing recombinant protein and its release (embodiments) is disclosed. But, the method is not suitable for the use of human cells, as it requires a large number of cells to be harvested from a frozen cellular bank.