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Wen cai Li
Researcher at Zhengzhou University
Publications - 2
Citations - 100
Wen cai Li is an academic researcher from Zhengzhou University. The author has contributed to research in topics: ATRX & PDGFRA. The author has an hindex of 2, co-authored 2 publications receiving 52 citations.
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IDH mutant lower grade (WHO Grades II/III) astrocytomas can be stratified for risk by CDKN2A, CDK4 and PDGFRA copy number alterations
Rui Ryan Yang,Zhi feng Shi,Zhen-Yu Zhang,Aden Ka-Yin Chan,Abudumijiti Aibaidula,Wei wei Wang,Johnny S. H. Kwan,Wai Sang Poon,Hong Chen,Wen cai Li,Nellie Yuk Fei Chung,Gopika Punchhi,William Ching Yuen Chu,Ivan Sik Hei Chan,Xian zhi Liu,Ying Mao,Kay Ka Wai Li,Ho Keung Ng +17 more
TL;DR: The data illustrate that IDH mutant lower grade astrocytomas is not a homogeneous group and should be molecularly stratified for risk, and these alterations occurred in a mutually exclusive fashion.
Journal ArticleDOI
Pediatric low-grade gliomas can be molecularly stratified for risk.
Rui Ryan Yang,Rui Ryan Yang,Abudumijiti Aibaidula,Wei wei Wang,Aden Ka-Yin Chan,Zhi feng Shi,Zhen-Yu Zhang,Danny Tat Ming Chan,Wai Sang Poon,Xian zhi Liu,Wen cai Li,Rui qi Zhang,Yan Xi Li,Nellie Yuk Fei Chung,Hong Chen,Jingsong Wu,Liangfu Zhou,Kay Ka Wai Li,Ho Keung Ng +18 more
TL;DR: Survival analysis revealed that TERTp mutation, H3F3A mutation, and ATRX loss were significantly associated with poor PFS, and it was shown that these molecular biomarkers can be used to stratify PLGGs into low- (KIAA1549-BRAF fusion or MYB amplification), intermediate-I, intermediate-II, and high-risk groups with distinct PFS.