H
Ho Keung Ng
Researcher at The Chinese University of Hong Kong
Publications - 302
Citations - 17476
Ho Keung Ng is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Loss of heterozygosity & Glioma. The author has an hindex of 59, co-authored 284 publications receiving 12031 citations. Previous affiliations of Ho Keung Ng include Hong Kong University of Science and Technology.
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Journal ArticleDOI
The 2021 WHO Classification of Tumors of the Central Nervous System: a summary.
David N. Louis,Arie Perry,Pieter Wesseling,Daniel J. Brat,Ian A. Cree,Dominique Figarella-Branger,Cynthia Hawkins,Ho Keung Ng,Stefan M. Pfister,Guido Reifenberger,Riccardo Soffietti,Andreas von Deimling,Andreas von Deimling,David W. Ellison +13 more
TL;DR: The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), published in 2021, is the sixth version of the international standard for the classification of brain and spinal cord tumors as mentioned in this paper.
Journal ArticleDOI
Intertumoral Heterogeneity within Medulloblastoma Subgroups
Florence M.G. Cavalli,Marc Remke,Marc Remke,Marc Remke,Ladislav Rampášek,John Peacock,David Shih,Betty Luu,Livia Garzia,Jonathon Torchia,Carolina Nor,A. Sorana Morrissy,Sameer Agnihotri,Yuan Yao Thompson,Claudia M. Kuzan-Fischer,Hamza Farooq,Keren Isaev,Keren Isaev,Craig Daniels,Byung Kyu Cho,Seung-Ki Kim,Kyu-Chang Wang,Ji Yeoun Lee,Wiesława Grajkowska,Marta Perek-Polnik,Alexandre Vasiljevic,Cécile Faure-Conter,Anne Jouvet,Caterina Giannini,Amulya A. Nageswara Rao,Kay Ka Wai Li,Ho Keung Ng,Charles G. Eberhart,Ian F. Pollack,Ronald L. Hamilton,G. Yancey Gillespie,James M. Olson,James M. Olson,Sarah Leary,William A. Weiss,Boleslaw Lach,Boleslaw Lach,Lola B. Chambless,Reid C. Thompson,Michael K. Cooper,Rajeev Vibhakar,Peter Hauser,Marie Lise C. van Veelen,Johan M. Kros,Pim J. French,Young Shin Ra,Toshihiro Kumabe,Enrique López-Aguilar,Karel Zitterbart,Jaroslav Sterba,Gaetano Finocchiaro,Maura Massimino,Erwin G. Van Meir,Satoru Osuka,Tomoko Shofuda,Almos Klekner,Massimo Zollo,Jeffrey R. Leonard,Joshua B. Rubin,Nada Jabado,Steffen Albrecht,Steffen Albrecht,Jaume Mora,Timothy E. Van Meter,Shin Jung,Andrew S. Moore,Andrew R. Hallahan,Jennifer A. Chan,Daniela Pretti da Cunha Tirapelli,Carlos Gilberto Carlotti,Maryam Fouladi,José Pimentel,Claudia C. Faria,Ali G. Saad,Luca Massimi,Linda M. Liau,Helen Wheeler,Hideo Nakamura,Samer K. Elbabaa,Mario Perezpeña-Diazconti,Fernando Chico Ponce de León,Shenandoah Robinson,Michal Zapotocky,Alvaro Lassaletta,Annie Huang,Cynthia Hawkins,Uri Tabori,Eric Bouffet,Ute Bartels,Peter B. Dirks,James T. Rutka,Gary D. Bader,Jüri Reimand,Jüri Reimand,Anna Goldenberg,Vijay Ramaswamy,Michael D. Taylor +101 more
TL;DR: Similarity network fusion (SNF) applied to genome-wide DNA methylation and gene expression data across 763 primary samples identifies very homogeneous clusters of patients, supporting the presence of medulloblastoma subtypes.
Journal ArticleDOI
Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma
Alan Mackay,Anna Burford,Diana Carvalho,Elisa Izquierdo,Janat Fazal-Salom,Kathryn R. Taylor,Kathryn R. Taylor,Lynn Bjerke,Matthew Clarke,Mara Vinci,Meera Nandhabalan,Sara Temelso,Sergey Popov,Sergey Popov,Valeria Molinari,Pichai Raman,Angela J. Waanders,Harry J. Han,Saumya Gupta,Lynley V. Marshall,Stergios Zacharoulis,Sucheta Vaidya,Henry Mandeville,Leslie R. Bridges,Andrew J. Martin,Safa Al-Sarraj,Christopher Chandler,Ho Keung Ng,Xingang Li,Kun Mu,Saoussen Trabelsi,Dorra H'mida-Ben Brahim,Alexei N. Kisljakov,Dmitry M. Konovalov,Andrew S. Moore,Angel M. Carcaboso,Mariona Suñol,Carmen Torres,Ofelia Cruz,Jaume Mora,Ludmila I. Shats,João Norberto Stávale,Lucas Tadeu Bidinotto,Rui Manuel Reis,Natacha Entz-Werle,Michael A. Farrell,Jane Cryan,Darach Crimmins,John Caird,Jane Pears,Michelle Monje,Marie-Anne Debily,David Castel,Jacques Grill,Cynthia Hawkins,Hamid Nikbakht,Nada Jabado,Suzanne J. Baker,Stefan M. Pfister,Stefan M. Pfister,David T.W. Jones,Maryam Fouladi,André O. von Bueren,André O. von Bueren,Michael Baudis,Adam C. Resnick,Chris Jones +66 more
TL;DR: Genomic aberrations increase with age, highlighting the infant population as biologically and clinically distinct, and co-segregating mutations in histone-mutant subgroups including loss of FBXW7 in H 3.3G34R/V, TOP3A rearrangements in H3.3K27M, and BCOR mutations in H2.1K 27M are identified.
Journal ArticleDOI
International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading
David N. Louis,Arie Perry,Peter C. Burger,David W. Ellison,Guido Reifenberger,Andreas von Deimling,Kenneth Aldape,Daniel J. Brat,V. Peter Collins,Charles G. Eberhart,Dominique Figarella-Branger,Gregory N. Fuller,Felice Giangaspero,Caterina Giannini,Cynthia Hawkins,Paul Kleihues,Andrey Korshunov,Johan M. Kros,M. Beatriz S. Lopes,Ho Keung Ng,Hiroko Ohgaki,Werner Paulus,Torsten Pietsch,Marc K. Rosenblum,Elisabeth J. Rushing,Figen Soylemezoglu,Otmar D. Wiestler,Pieter Wesseling +27 more
TL;DR: The present “white paper” catalogs the recommendations of the meeting, at which a consensus was reached that incorporation of molecular information into the next WHO classification of central nervous system tumors should follow a set of provided “ISN‐Haarlem” guidelines.
Journal ArticleDOI
cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading.
David N. Louis,Pieter Wesseling,Kenneth Aldape,Daniel J. Brat,David Capper,David Capper,Ian A. Cree,Charles G. Eberhart,Dominique Figarella-Branger,Maryam Fouladi,Gregory N. Fuller,Caterina Giannini,Caterina Giannini,Christine Haberler,Cynthia Hawkins,Takashi Komori,Johan M. Kros,Ho Keung Ng,Brent A. Orr,Sung Hye Park,Werner Paulus,Arie Perry,Torsten Pietsch,Guido Reifenberger,Marc K. Rosenblum,Brian Rous,Brian Rous,Felix Sahm,Felix Sahm,Chitra Sarkar,David A. Solomon,Uri Tabori,Martin J. van den Bent,Andreas von Deimling,Andreas von Deimling,Michael Weller,Valerie A. White,David Ellison +37 more
TL;DR: Working Committee 3 recommended that a substantial number of newly recognized types and subtypes should be considered for inclusion in future CNS tumor classifications.