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Nellie Yuk Fei Chung
Researcher at The Chinese University of Hong Kong
Publications - 24
Citations - 777
Nellie Yuk Fei Chung is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Oligodendroglial Tumor & Medicine. The author has an hindex of 13, co-authored 21 publications receiving 578 citations. Previous affiliations of Nellie Yuk Fei Chung include Chinese Academy of Sciences.
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Adult IDH wild-type lower-grade gliomas should be further stratified.
Abudumijit Aibaidula,Aden Ka-Yin Chan,Zhifeng Shi,Yanxi Li,Rui-qi Zhang,Rui Ryan Yang,Kay Ka-Wai Li,Nellie Yuk Fei Chung,Yu Yao,Liangfu Zhou,Jinsong Wu,Hong Chen,Ho Keung Ng +12 more
TL;DR: Adult IDH wild-type lower-grade gliomas are prognostically heterogeneous and do not have uniformly poor prognosis.
Journal ArticleDOI
Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion
Kin-Mang Lau,Queeny Kwan Yi Chan,Jesse Chung Sean Pang,Kay Ka-Wai Li,Walter Wai Yeung,Nellie Yuk Fei Chung,Philip C.W. Lui,Y. S. Tam,Hiu-Ming Li,Liangfu Zhou,Yitao Wang,Ying Mao,Ho Keung Ng +12 more
TL;DR: Deregulation of MCM2, MCM3 and MCM7 expression might be involved in MB tumorigenesis and undefined roles of these MCMs in control of MB cell migration and invasion are revealed.
Journal ArticleDOI
TERT promoter mutations contribute to subset prognostication of lower-grade gliomas
Aden Ka-Yin Chan,Yu Yao,Zhen-Yu Zhang,Nellie Yuk Fei Chung,Joseph Shu Ming Liu,Kay Ka Wai Li,Zhifeng Shi,Danny Tat Ming Chan,Wai Sang Poon,Liangfu Zhou,Ho Keung Ng +10 more
TL;DR: It is indicated that when combined with IDH status, TERT promoter mutation contributes to prognostic subgroups of lower-grade astrocytic tumors or 1p/19q intact lower- grade gliomas and this may further refine future molecular classification of lower toastrocytomas.
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IDH mutant lower grade (WHO Grades II/III) astrocytomas can be stratified for risk by CDKN2A, CDK4 and PDGFRA copy number alterations
Rui Ryan Yang,Zhi feng Shi,Zhen-Yu Zhang,Aden Ka-Yin Chan,Abudumijiti Aibaidula,Wei wei Wang,Johnny S. H. Kwan,Wai Sang Poon,Hong Chen,Wen cai Li,Nellie Yuk Fei Chung,Gopika Punchhi,William Ching Yuen Chu,Ivan Sik Hei Chan,Xian zhi Liu,Ying Mao,Kay Ka Wai Li,Ho Keung Ng +17 more
TL;DR: The data illustrate that IDH mutant lower grade astrocytomas is not a homogeneous group and should be molecularly stratified for risk, and these alterations occurred in a mutually exclusive fashion.
Journal ArticleDOI
Loss of CIC and FUBP1 expressions are potential markers of shorter time to recurrence in oligodendroglial tumors.
Aden Ka-Yin Chan,Jesse Chung Sean Pang,Nellie Yuk Fei Chung,Kay Ka Wai Li,Wai Sang Poon,Danny Tat Ming Chan,Zhifeng Shi,Liang Chen,Liangfu Zhou,Ho Keung Ng +9 more
TL;DR: It is concluded that absent CIC and FUBP1 expressions are potential markers of shorter time to recurrence and CIC mutation a potential marker of worse prognosis, especially in tumors carrying 1p/19q codeletion.