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Wen-jing Yi
Researcher at Second Military Medical University
Publications - 5
Citations - 243
Wen-jing Yi is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Sepsis & Lung injury. The author has an hindex of 5, co-authored 5 publications receiving 181 citations.
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Journal ArticleDOI
Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1β Axis in Microglia.
Da-ming Sui,Qun Xie,Wen-jing Yi,Sahil Gupta,Xiya Yu,Jinbao Li,Jun Wang,Jiafeng Wang,Xiaoming Deng +8 more
TL;DR: It is shown that resveratrol improves the spatial memory in mice with SAE and inhibits the NLRP3/IL-1β axis in the microglia and prevents ATP inducedNLRP3 activation and IL-1 β cleavage in the BV2 cell lines.
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Up-regulation of programmed cell death 1 ligand 1 on neutrophils may be involved in sepsis-induced immunosuppression: an animal study and a prospective case-control study.
Jiafeng Wang,Jin-Bao Li,Yan-jun Zhao,Wen-jing Yi,Jin-jun Bian,Xiao-Jian Wan,Ke-ming Zhu,Xiaoming Deng +7 more
TL;DR: PD-L1 is up-regulated on neutrophils during sepsis, which may be related to sepsi-induced immunosuppression.
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miR-98 protects endothelial cells against hypoxia/reoxygenation induced-apoptosis by targeting caspase-3.
TL;DR: Renal IRI induces up-regulation of miR-98 dependent on HIF-1α, which protects endothelial cells against apoptosis by targeting caspase-3, and the dual-luciferase reporter assay confirmed that mi R-98 decreased the luciferase activity by targeting the 3' untranslated region of casp enzyme.
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Blockade of ICAM-1 improves the outcome of polymicrobial sepsis via modulating neutrophil migration and reversing immunosuppression.
Yan-jun Zhao,Wen-jing Yi,Xiaojian Wan,Jun Wang,Tianzhu Tao,Jinbao Li,Jiafeng Wang,Xiaoming Deng +7 more
TL;DR: In conclusion, ICAM-1 blockade may improve outcome of sepsis and may include the modulated neutrophil migration and the reversed immunosuppression.
Journal ArticleDOI
Dual role of leukotriene B4 receptor type 1 in experimental sepsis.
Xiu-juan Li,Hong-yu Fu,Wen-jing Yi,Yan-jun Zhao,Jun Wang,Jinbao Li,Jiafeng Wang,Xiaoming Deng +7 more
TL;DR: U-75302 attenuates sepsis-induced organ injury, whereas L TB4 increases the leukocyte recruitment toward infection site, but LTB4 showed a more lethal effect than U-75 302 during polymicrobial sepsi.