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Wendell F. Rosse
Researcher at Duke University
Publications - 158
Citations - 14282
Wendell F. Rosse is an academic researcher from Duke University. The author has contributed to research in topics: Paroxysmal nocturnal hemoglobinuria & Antibody. The author has an hindex of 56, co-authored 158 publications receiving 13682 citations. Previous affiliations of Wendell F. Rosse include Baylor College of Medicine & University of Washington.
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Journal ArticleDOI
Mortality In Sickle Cell Disease -- Life Expectancy and Risk Factors for Early Death
Orah S. Platt,Donald Brambilla,Wendell F. Rosse,Paul F. Milner,Oswaldo Castro,Martin H. Steinberg,Panpit P. Klug +6 more
TL;DR: Modeling revealed that in patients with sickle cell anemia, the acute chest syndrome, renal failure, seizures, a base-line white-cell count above 15,000 cells per cubic millimeter, and a low level of fetal hemoglobin were associated with an increased risk of early death.
Journal ArticleDOI
Pain in sickle cell disease. Rates and risk factors.
Orah S. Platt,Bruce D. Thorington,Donald Brambilla,Paul F. Milner,Wendell F. Rosse,Elliott Vichinsky,Thomas R. Kinney +6 more
TL;DR: The "pain rate" is a measure of clinical severity and correlates with early death in patients with sickle cell anemia over the age of 20, and even when the fetal hemoglobin level is low, one can predict that small increments in the level may have an ameliorating effect on the pain rate and may ultimately improve survival.
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Diagnosis and management of paroxysmal nocturnal hemoglobinuria.
Charles J. Parker,Mitsuhiro Omine,Stephen J. Richards,Junichi Nishimura,Monica Bessler,Russell E. Ware,Peter Hillmen,Lucio Luzzatto,Neal S. Young,Taroh Kinoshita,Wendell F. Rosse,Gérard Socié +11 more
TL;DR: The primary clinical manifestations of paroxysmal nocturnal hemoglobinuria are hemolytic anemia, marrow failure, and thrombophilia.
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Quantitative determination of antibody in idiopathic thrombocytopenic purpura. Correlation of serum and platelet-bound antibody with clinical response.
TL;DR: Quantitation of surface IgG of thrombocytopenic platelets was useful in predicting response to treatment and correlated with failure to respond to prednisone therapy.
Journal ArticleDOI
Transfusion and alloimmunization in sickle cell disease. The Cooperative Study of Sickle Cell Disease
Wendell F. Rosse,Dianne Gallagher,Thomas R. Kinney,Oswaldo Castro,Harvey Dosik,John Moohr,Winfred C. Wang,Paul S. Levy +7 more
TL;DR: Patients with sickle cell disease who had been transfused were more frequently alloimmunized than men; this was largely due to the fact that women received more transfusions than men, but in the age group 16 to 20 years the increase may have been due in part to alloIMmunization owing to pregnancy.