W
Wendy Graham
Researcher at Harvard University
Publications - 14
Citations - 787
Wendy Graham is an academic researcher from Harvard University. The author has contributed to research in topics: Biodistribution & 3-Iodobenzylguanidine. The author has an hindex of 12, co-authored 14 publications receiving 773 citations. Previous affiliations of Wendy Graham include Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Enhancement of fluid filtration across tumor vessels: Implication for delivery of macromolecules
Paolo A. Netti,Leena Hamberg,John W. Babich,Diane Kierstead,Wendy Graham,George J. Hunter,Gerald L. Wolf,Alan J. Fischman,Yves Boucher,Rakesh K. Jain +9 more
TL;DR: It is postulate that modulation of tumor microvascular pressure (MVP) and associated changes in IFP would enhance macromolecular delivery into a solid tumor.
Journal ArticleDOI
Rapid detection of Parkinson's disease by SPECT with altropane: A selective ligand for dopamine transporters
Alan J. Fischman,Ali A. Bonab,John W. Babich,E. Prather Palmer,Nathaniel M. Alpert,David R. Elmaleh,Ronald J. Callahan,Sandra A. Barrow,Wendy Graham,Peter C. Meltzer,Robert N. Hanson,Bertha K. Madras +11 more
TL;DR: SPECT images in healthy volunteers showed that [123I]altropane accumulated rapidly and selectively in the striatum and yielded excellent quality images within 1 h after injection, and plasma analysis indicated that [ 123I]ALTropane is rapidly converted to polar metabolites.
Journal Article
Technetium-99m-labeled hydrazino nicotinamide derivatized chemotactic peptide analogs for imaging focal sites of bacterial infection.
John W. Babich,Howard F. Solomon,Marilyn C. Pike,Kroon Daniel J,Wendy Graham,Michael J. Abrams,Ronald G. Tompkins,Robert H. Rubin,Alan J. Fischman +8 more
TL;DR: It is demonstrated that 99mTc-labeled chemotactic peptide analogs are effective agents for the external imaging of focal sites of infection in rats and rabbits.
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Synthesis and Characterization of Organohydrazino Complexes of Technetium, Rhenium, and Molybdenum with the {M(η1-HxNNR)(η2-HyNNR)} Core and Their Relationship to Radiolabeled Organohydrazine-Derivatized Chemotactic Peptides with Diagnostic Applications
David J. Rose,Kevin P. Maresca,Terrence Nicholson,A. Davison,Alun G. Jones,John W. Babich,Alan Fischman,Wendy Graham,Jeffery R. D. DeBord,Jon Zubieta +9 more
TL;DR: The reduction of perrhenate, molybdate and pertechnetate with 2-hydrazinopyridine dihydrochloride in methanol has led to the preparation of a class of complexes containing the M(eta(1)-NNC(5)H(4)NH(x)())(eta(2)-HNNH(y)().
Journal Article
Technetium-99m-labeled chemotactic peptides: comparison with indium-111-labeled white blood cells for localizing acute bacterial infection in the rabbit.
John W. Babich,Wendy Graham,Sandra A. Barrow,Stephen C. Dragotakes,Ronald G. Tompkins,Robert H. Rubin,Alan J. Fischman +6 more
TL;DR: Results indicate that 99mTc-HP yields target-to-background ratios greater than or equal to those achievable with 111In-WBCs probably as a result of an increase in absolute accumulation at the site of infection.