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Wenwen Wu
Researcher at Central South University
Publications - 4
Citations - 83
Wenwen Wu is an academic researcher from Central South University. The author has contributed to research in topics: Kidney & Renal fibrosis. The author has an hindex of 1, co-authored 4 publications receiving 8 citations.
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Journal ArticleDOI
Discovery and validation of miR-452 as an effective biomarker for acute kidney injury in sepsis.
Zhiwen Liu,Danyi Yang,Gao Jingli,Xiaohong Xiang,Xiaoru Hu,Siyao Li,Wenwen Wu,Juan Cai,Chengyuan Tang,Dongshan Zhang,Zheng Dong +10 more
TL;DR: In this paper, miR-452 was induced in renal tubular cells in septic acute kidney injury (AKI) and the induction was shown to be mediated by NF-κB.
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Reciprocal regulation between ER stress and autophagy in renal tubular fibrosis and apoptosis.
Shaoqun Shu,Hui Wang,Jiefu Zhu,Zhiwen Liu,Danyi Yang,Wenwen Wu,Juan Cai,Anqun Chen,Chengyuan Tang,Zheng Dong,Zheng Dong +10 more
TL;DR: In this article, a mouse model of ER stress-induced chronic kidney injury by 2 weekly injections of a low dose of tunicamycin (TM), a classical endoplasmic reticulum (ER) stress inducer, was established.
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NAM protects against cisplatin-induced acute kidney injury by suppressing the PARP1/p53 pathway
Wenwen Wu,Ying Fu,Zhiwen Liu,Shaoqun Shu,Ying Wang,Chengyuan Tang,Juan Cai,Zheng Dong,Zheng Dong +8 more
TL;DR: In this article, the authors suggest that nicotinamide may protect against acute kidney injury (AKI) mainly via suppressing the poly ADP-ribose polymerase 1 (PARP1)/p53 pathway.
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PARK7 Protects Against Chronic Kidney Injury and Renal Fibrosis by Inducing SOD2 to Reduce Oxidative Stress.
TL;DR: Park disease protein 7 (PARK7) is a multifunctional protein involved in various cellular processes, but its pathophysiological role in kidneys remain largely unknown as mentioned in this paper, and Park7 deficiency aggravated UUO-induced renal fibrosis, tubular cell apoptosis, ROS production and inflammation.