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Wesley B. Baker
Researcher at Children's Hospital of Philadelphia
Publications - 82
Citations - 2262
Wesley B. Baker is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Cerebral blood flow & Medicine. The author has an hindex of 19, co-authored 62 publications receiving 1645 citations. Previous affiliations of Wesley B. Baker include Hospital of the University of Pennsylvania & University of Pennsylvania.
Papers
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Journal ArticleDOI
Diffuse optics for tissue monitoring and tomography
TL;DR: The theoretical basis for near-infrared or diffuse optical spectroscopy (NIRS or DOS) is developed, and the basic elements of diffuse optical tomography (DOT) are outlined.
Journal ArticleDOI
Modified Beer-Lambert law for blood flow
Wesley B. Baker,Ashwin B. Parthasarathy,David R. Busch,Rickson C. Mesquita,Joel H. Greenberg,Arjun G. Yodh +5 more
TL;DR: A Modified Beer-Lambert law for blood flow based on diffuse correlation spectroscopy (DCS) measurements is developed and validated and is particularly well-suited for utilization with pressure measurement paradigms that employ differential flow signals to reduce contributions of superficial tissues.
Journal ArticleDOI
Fast blood flow monitoring in deep tissues with real-time software correlators.
Wang Detian,Ashwin B. Parthasarathy,Wesley B. Baker,Kimberly Gannon,Venki Kavuri,Tiffany Ko,Steven S. Schenkel,Zhe Li,Zeren Li,Michael T. Mullen,John A. Detre,Arjun G. Yodh +11 more
TL;DR: The device to separate tissue blood flow from tissue absorption/scattering dynamics is employed and it is shown that the origin of the pulsatile DCS signal is primarily flow, and cerebral autoregulation dynamics in healthy volunteers are monitored more accurately than with traditional instrumentation as a result of increased data acquisition rates.
Journal ArticleDOI
Pressure modulation algorithm to separate cerebral hemodynamic signals from extracerebral artifacts.
Wesley B. Baker,Ashwin B. Parthasarathy,Tiffany Ko,David R. Busch,David R. Busch,Kenneth Abramson,Shih Yu Tzeng,Shih Yu Tzeng,Rickson C. Mesquita,Turgut Durduran,Joel H. Greenberg,David Kung,Arjun G. Yodh +12 more
TL;DR: The algorithm’s ability to isolate cerebral blood flow during a finger-tapping task and during graded scalp ischemia in healthy adults is demonstrated and the algorithm is adapted to ameliorate extracerebral contamination in monitoring of cerebral blood oxygenation and blood volume by near-infrared spectroscopy.
Journal ArticleDOI
The effect of right vagus nerve stimulation on focal cerebral ischemia: an experimental study in the rat
TL;DR: VNS offers neuroprotection against stroke in both temporary and permanent ischemia, although the precise mechanism of this effect remains to be determined, alterations in cerebral blood flow do not appear to play a role.