William E. Alborn

TL;DR: In the analysis of the genome, a large number of new uncharacterized genes predicted to encode proteins that either reside on the surface of the cell or are secreted are identified and there may be new targets for vaccine and antibiotic development.

TL;DR: The results suggest that the addition of a PCSK9 inhibitor to statin therapy may result in even further LDL-C decreases, which are currently seen in patients treated with atorvastatin.

TL;DR: The evidence indicates that the bactericidal activity of daptomycin is dependent on an available delta psi, and may account for many of the inhibitory effects on macromolecular biosyntheses and membrane function reported for this antibiotic.

TL;DR: These data demonstrate for the first time that ApoA5 is a secreted protein present in human serum and is associated with specific lipoprotein particles, and indicate that the circulating concentration of human Apo A5 is very low compared with other apolipoproteins.

TL;DR: PCSK9 is present in human serum, likely not associated with specific lipoprotein particles, and the circulating concentrations of human PCSK9 are directly correlated with LDL and total cholesterol concentrations.