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William H. Fishman
Researcher at Tufts University
Publications - 143
Citations - 5822
William H. Fishman is an academic researcher from Tufts University. The author has contributed to research in topics: Alkaline phosphatase & Glucuronidase. The author has an hindex of 40, co-authored 143 publications receiving 5796 citations. Previous affiliations of William H. Fishman include Tufts Medical Center.
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Journal Article
A Serum Alkaline Phosphatase Isoenzyme of Human Neoplastic Cell Origin
TL;DR: The possibility that elevated serum alkaline phosphatase in patients with metastatic cancer can be of neoplastic rather than of hepatic and osseous origin is demonstrated.
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Immunology and biochemistry of Regan isoenzyme of alkaline phosphatase in human cancer.
William H. Fishman,Norma R. Inglis,Sidney Green,Claire L. Anstiss,Nimai K. Gosh,Arnold E. Reif,Robert Rustigian,Melvin J. Krant,Leo L. Stolbach +8 more
TL;DR: Derepression of the genome of the cancer cell may explain why certain cancer patients exhibit an isoenzyme of alkalineosphatase biochemically and immunologically indistinguishable from human placental alkaline phosphatase.
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A method for estimating serum acid phosphatase of prostatic origin.
William H. Fishman,F. Lerner +1 more
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Ectopic Production of an Alkaline Phosphatase Isoenzyme in Patients with Cancer
TL;DR: An alkaline phosphatase isoen enzyme (Regan isoenzyme) has been identified in the serum of 27 patients with various malignant tumors and has been clinically useful in monitoring progression or regression of tumor, identifying a source of serum alkaline phosphate elevation, and identifying malignant effusions.
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L -Phenylalanine : an Organ Specific, Stereo-specific Inhibitor of Human Intestinal Alkaline Phosphatase
TL;DR: HUMAN alkaline phosphatase of intestine but not of liver, bile, bone, lung, kidney and spleen is almost completely inhibited by L-phenylalanine and is not so affected by D-phenYLalanine.