W
William J. Tremaine
Researcher at Mayo Clinic
Publications - 290
Citations - 26053
William J. Tremaine is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Ulcerative colitis & Inflammatory bowel disease. The author has an hindex of 80, co-authored 282 publications receiving 24233 citations. Previous affiliations of William J. Tremaine include University of Paris & Cedars-Sinai Medical Center.
Papers
More filters
Journal ArticleDOI
Management of Crohn's disease of the ileoanal pouch with infliximab☆
Jean-Frederic Colombel,Elena Ricart,Edward V. Loftus,William J. Tremaine,Tonia M. Young-Fadok,Eric J. Dozois,Bruce G. Wolff,Richard M. Devine,John H. Pemberton,William J. Sandborn +9 more
TL;DR: Infliximab is beneficial in both the short and long term treatment of patients with an IPAA performed for a presumed diagnosis of ulcerative colitis who subsequently develop CD-related complications.
Journal ArticleDOI
Measurement of serum 7α-hydroxy-4-cholesten-3-one (or 7αC4), a surrogate test for bile acid malabsorption in health, ileal disease and irritable bowel syndrome using liquid chromatography-tandem mass spectrometry
Michael Camilleri,Ashley Nadeau,William J. Tremaine,Jesse Lamsam,Duane Burton,Suwebatu T. Odunsi,Seth Sweetser,Ravinder J. Singh +7 more
TL;DR: A sensitive non‐isotopic assay based on HPLC‐MS/MS is established, normal 7αC4 values are determined, and increased 7 αC4 in IBS‐D and in distal ileal resection and disease is identified.
Journal ArticleDOI
Evaluation of serologic disease markers in a population-based cohort of patients with ulcerative colitis and Crohn's disease
William J. Sandborn,Edward V. Loftus,Jean-Frederic Colombel,Kenneth A. Fleming,Frank Seibold,Henry A. Homburger,Boualem Sendid,Roger W. Chapman,William J. Tremaine,Debra K. Kaul,Jeannie S. Wallace,William S. Harmsen,Alan R. Zinsmeister,Stephan R. Targan +13 more
TL;DR: In patients with IBD, the sensitivity of ANCA varied widely in different laboratories, whereas the prevalence of ASCA was similar, and the positive predictive values of the ANCA assay combined with the ASCA assay for ulcerative colitis and Crohn's disease are high enough to be clinically useful.
Journal ArticleDOI
Risk of lymphoma in inflammatory bowel disease.
Edward V. Loftus,William J. Tremaine,Thomas M. Habermann,W. Scott Harmsen,Alan R. Zinsmeister,William J. Sandborn +5 more
TL;DR: It is demonstrated that the absolute risk of non-Hodgkin’s lymphoma remains quite small (0.01% per person-year) and may not exceed that in the general population.
Journal Article
Antineutrophil cytoplasmic antibody correlates with chronic pouchitis after ileal pouch-anal anastomosis.
TL;DR: The finding that perinuclear antineutrophil cytoplasmic antibodies occur more frequently in patients with chronic pouchitis raises the possibility that this antibody may mark a genetically distinct subset of ulcerative colitis patients.