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William Même
Researcher at Centre national de la recherche scientifique
Publications - 24
Citations - 588
William Même is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Skeletal muscle & Hippocampal formation. The author has an hindex of 12, co-authored 24 publications receiving 455 citations. Previous affiliations of William Même include University of Orléans.
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Journal ArticleDOI
Characterization of human monocyte-derived microglia-like cells.
Cathie Léone,Gwenaelle Le Pavec,William Même,Fabrice Porcheray,Boubekeur Samah,Dominique Dormont,Gabriel Gras +6 more
TL;DR: A convenient cellular model for human microglia, suitable for HIV studies, is developed from human monocytes and may help to better understand HIV‐associated microgliosis and chronic inflammation in the brain.
Journal ArticleDOI
Chronic exposure to glufosinate-ammonium induces spatial memory impairments, hippocampal MRI modifications and glutamine synthetase activation in mice.
André-Guilhem Calas,Olivier Richard,Sandra Même,Jean-Claude Beloeil,Bich-Thuy Doan,Thierry Gefflaut,William Même,Wim E. Crusio,Jacques Pichon,Céline Montécot +9 more
TL;DR: The present study provides the first data that show cerebral alterations after chronic exposure to GLA, and it is suggested that these modifications may be causally linked one to another.
Journal ArticleDOI
Electrical coupling between hippocampal astrocytes in rat brain slices.
TL;DR: It is demonstrated that hippocampal astrocytes are electrically coupled through gap-junction channels characterized by properties that are distinct from those of electrical synapses between neurons, and gap-Junctional communication is efficiently regulated by endogenous compounds.
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IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria.
Flora Reverchon,Flora Reverchon,Stéphane Mortaud,Stéphane Mortaud,Maëliss Sivoyon,Maëliss Sivoyon,Isabelle Maillet,Isabelle Maillet,Anthony Laugeray,Anthony Laugeray,Jennifer Palomo,Jennifer Palomo,Céline Montécot,Céline Montécot,Ameziane Herzine,Ameziane Herzine,Sandra Même,William Même,François Erard,François Erard,Bernhard Ryffel,Bernhard Ryffel,Arnaud Menuet,Arnaud Menuet,Valérie F. J. Quesniaux,Valérie F. J. Quesniaux +25 more
TL;DR: Results highlight the IL-33/ST2 pathway ability to orchestrate microglia and oligodendrocytes responses at an early stage of PbA-infection, with an amplification loop between IL-1β and IL- 33, responsible for an exacerbated neuroinflammation context and associated neurological and cognitive defects.
Journal ArticleDOI
Cyclopiazonic acid-induced changes in the contraction and Ca2+ transient of frog fast-twitch skeletal muscle
TL;DR: It is concluded that CPA effects, at a concentration of up to 2 μM, were associated with specific inhibition of sarcoplasmic reticulum Ca2-adenosinetriphosphatase in intact skeletal muscle and that inhibition of the pump directly affected the handling of intracellular Ca2+ and force production.