William Tottey

TL;DR: An updated census of the archaeal diversity associated with the human GIT and their possible role in the gut physiology and health is provided and particularly focuses on the still poorly characterized 7th order of methanogens, the Methanomassiliicoccales associated to aged population.

TL;DR: This study represents the first insights into the genomic organization and metabolic traits of the seventh order of methanogens and suggests a different handling of the Pyl-encoding capacity among the three analyzed Methanomassiliicoccales representatives.

TL;DR: It is suggested that members of a recently discovered group of methanogens, that are variably present in the human gut, are unusual in being apparently restricted to utilizing only methyl compounds including TMA as substrates, and could be used as treatments for metabolic disorders.

TL;DR: The draft genome sequence of "Candidatus Methanomethylophilus alvus" Mx1201, a methanogen present in the human gut, is reported, which contains genes needed for methylotrophic methanogenesis from methanol and tri-, di-, and monomethylamine.

TL;DR: An explanation as to why germ-free rats are more efficient recipients and retainers of human microbiota than mice is offered and experimental design should take into account dynamic changes in the microbiota of model animals considering that their changing gut microbiota interacts with their physiology.