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Wolfgang Göhde

Researcher at University of Münster

Publications -  111
Citations -  4629

Wolfgang Göhde is an academic researcher from University of Münster. The author has contributed to research in topics: Flow cytometry & In vivo. The author has an hindex of 33, co-authored 111 publications receiving 4575 citations. Previous affiliations of Wolfgang Göhde include University of Hamburg & University of Texas MD Anderson Cancer Center.

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Journal Article

Flow Cytometry in Clinical Cancer Research

TL;DR: A role for flow cytometry is emerging as a tool for diagnosis of cancer (abnormal DNA content), specific histopathological diagnosis (RNA for hematological cancers; surface markers for lymphoid and myeloid neoplasms), prognosis, and treatment (cytokinetically oriented, monoclonal antibodies, drug pharmacology).
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Analysis of PCP-data to determine the fraction of cells in the various phases of cell cycle.

TL;DR: Two different mathematical models for PCP-data evaluation and the autoradiographic method yielded results agreeing within statistical error, suitable for asynchronous cell populations with a low fraction of S-phase cells, and for partially synchronized cells and high S- phase fractions as well.
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Cellular DNA content as a marker of neoplasia in man.

TL;DR: It is concluded that flow cytometry of cellular DNA content is a rapid, objective, quantitative and sensitive method to determine a highly specific and stable tumor cell marker.
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Sex determination in dioecious plants Melandrium album and M. rubrum using high-resolution flow cytometry

TL;DR: The results indicated the possibility of diagnosing sex also in other heterogametic dioecious plants and the assay described here might be interesting in any area where rapid sex identification is required at an early stage of plant development.
Journal Article

Determination of Ploidy and Proliferative Characteristics of Human Solid Tumors by Pulse Cytophotometry

TL;DR: Pretreatment cycle stagerelated DNA distribution patterns varied considerably for the entire patient population and for each diagnostic subgroup, and no correlation between ploidy and proliferative cell characteristics was apparent.