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Wolfram H. Gerlich
Researcher at University of Giessen
Publications - 159
Citations - 8830
Wolfram H. Gerlich is an academic researcher from University of Giessen. The author has contributed to research in topics: Hepatitis B virus & HBsAg. The author has an hindex of 43, co-authored 155 publications receiving 8300 citations.
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Large surface proteins of hepatitis B virus containing the pre-s sequence.
TL;DR: Immunological cross-reactions showed that P39/GP42 is partially homologous to P24/GP27 and GP33/GP36, and a model is presented of how the open reading frame for the viral envelope leads to defined amounts of three different proteins.
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Statements from the Taormina expert meeting on occult hepatitis B virus infection.
Giovanni Raimondo,Jean-Pierre Allain,Maurizia Rossana Brunetto,Marie Annick Buendia,Ding-Shinn Chen,Massimo Colombo,Antonio Craxì,Francesco Donato,Carlo Ferrari,Giovanni Battista Gaeta,Wolfram H. Gerlich,Massimo Levrero,Stephen Locarnini,Thomas I. Michalak,Mario U. Mondelli,Jean-Michel Pawlotsky,Teresa Pollicino,Daniele Prati,Massimo Puoti,Didier Samuel,Daniel Shouval,Antonina Smedile,Giovanni Squadrito,Christian Trepo,Erica Villa,Hans Will,Alessandro Zanetti,Fabien Zoulim +27 more
TL;DR: Giovanni Raimondo*, Jean-Pierre Allain, Maurizia R. Brunetto, Marie-Annick Buendia, Ding-Shinn Chen, Massimo Colombo, Antonio Craxi, Francesco Donato, Carlo Ferrari, Giovanni B. Gaeta, Wolfram H. Gerlich,Massimo Levrero, Stephen Locarnini, Thomas Michalak, Mario U. Zanetti, Fabien Zoulim
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Short statement of the first European Consensus Conference on the treatment of chronic hepatitis B and C in HIV co-infected patients.
A. Alberti,Nathan Clumeck,Simon Collins,Wolfram H. Gerlich,Jens D Lundgren,Giorgio Palù,Peter Reiss,Rodolphe Thiébaut,Ola Weiland,Yazdan Yazdanpanah,Stefan Zeuzem +10 more
TL;DR: Despite recent advances in the management of hepatitis and HIV coinfection, there is no clear consensus among hepatology, infectious diseases and virology experts on treatment of co-infections and patient management.
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Nucleic Acid Testing to Detect HBV Infection in Blood Donors
Susan L. Stramer,Ulrike C. Wend,Daniel Candotti,Gregory A. Foster,F. Blaine Hollinger,Roger Y. Dodd,Jean-Pierre Allain,Wolfram H. Gerlich +7 more
TL;DR: Triplex nucleic acid testing detected potentially infectious HBV, along with HIV and HCV, during the window period before seroconversion, and HBV vaccination appeared to be protective, with a breakthrough subclinical infection occurring with non-A2 HBV subgenotypes and causing clinically inconsequential outcomes.
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Medical Virology of Hepatitis B: how it began and where we are now
TL;DR: The cloning and sequencing of the HBV genome in 1978 paved the way to understand the viral life cycle, and allowed development of efficient vaccines and drugs, and today’s hepatitis B vaccine was the first vaccine produced by gene technology.