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Giovanni Squadrito

Researcher at University of Messina

Publications -  215
Citations -  9268

Giovanni Squadrito is an academic researcher from University of Messina. The author has contributed to research in topics: Hepatitis B virus & Internal medicine. The author has an hindex of 45, co-authored 191 publications receiving 8285 citations.

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Occult hepatitis B virus infection

TL;DR: Much evidence suggests that hepatitis B virus can favour the progression of liver fibrosis and above all the development of hepatocellular carcinoma, and is an entity with world-wide diffusion.
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Occult hepatitis B virus infection in patients with chronic hepatitis C liver disease.

TL;DR: Occult hepatitis B infection occurs frequently in patients with chronic hepatitis C liver disease and may have clinical significance, and none of the sequenced HBV genomes had changes known to interfere with viral activity and gene expression.
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Hepatitis B Virus Replication Is Regulated by the Acetylation Status of Hepatitis B Virus cccDNA-Bound H3 and H4 Histones

TL;DR: The use of anti-acetyl-H4/-H3 specific antibodies to immunoprecipitate transcriptionally active chromatin revealed that HBV replication is regulated by the acetylation status of the cccDNA-bound H3/H4 histones.
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Hepatitis B virus maintains its pro-oncogenic properties in the case of Occult HBV infection

TL;DR: Clear evidence is provided that occult HBV is a risk factor for development of HCC and that the potential mechanisms whereby overt HBV might induce tumor formation are mostly maintained in cases of occult infection.