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Xavier Le Goff
Researcher at Centre national de la recherche scientifique
Publications - 37
Citations - 993
Xavier Le Goff is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Cytokinesis & Cell division. The author has an hindex of 11, co-authored 36 publications receiving 932 citations. Previous affiliations of Xavier Le Goff include ISREC & University of Rennes.
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A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor
Lyudmila Frolova,Lyudmila Frolova,Xavier Le Goff,Hanne H. Rasmussen,Sergey Cheperegin,Gabrièle Drugeon,Michel Kress,Inga P. Arman,Anne-Lise Haenni,Jullo E. Celis,Michel Phllippe,Just Justesen,Lev L. Kisselev +12 more
TL;DR: The assignment of a family of tightly related proteins from lower and higher eukaryotes which are structurally and functionally similar to rabbit eRF are reported, concluding that the eRFl proteins are directly implicated in the termination of translation in eukARYotes.
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Controlling septation in fission yeast: finding the middle, and timing it right.
TL;DR: Analysis of mutants has begun to shed light upon how septum formation and cytokinesis are regulated both spatially and temporally, suggesting that aspects of this control will be common to all eukaryotic cells.
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An overview of the KIN1/PAR-1/MARK kinase family.
TL;DR: An overview of known roles of KIN1/PAR‐1/MARK kinases including pEg3 a newly identified member which is regulated during the cell cycle and is a potential regulator of thecell cycle progression is presented.
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Eukaryotic release factor 1 (eRF1) abolishes readthrough and competes with suppressor tRNAs at all three termination codons in messenger RNA.
Gabrièle Drugeon,Olivier Jean-Jean,Lyudmila Frolova,Lyudmila Frolova,Xavier Le Goff,Michel Philippe,Lev L. Kisselev,Lev L. Kisselev,Anne-Lise Haenni +8 more
TL;DR: ERF1 is functional towards all three termination codons located in a natural mRNA and efficiently competes in vitro with endogenous and exogenous suppressor tRNA(s) at the ribosomal A site, consistent with a crucial role of eRF1 in translation termination.
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Fission yeast cytoskeletons and cell polarity factors: connecting at the cortex
TL;DR: Recent advances in knowledge of molecular pathways leading to the establishment of a cellular axis in fission yeast are reviewed and the role of cortical proteins and mitotic cytoskeletal rearrangements that control the symmetry of cell division are described.