Xian-Zhe Dong

TL;DR: The in vitro proliferation inhibition effect of SAN was determined using CCK-8 assay, and the in vivo antitumor effect of San was evaluated in mice with xenotransplanted tumor, indicating that SAN may inhibit the proliferation of BGC-823 cells through the inhibition ofmiR-96-5p and miR-29c-3p expression, and subsequent activation of the MAPK/JNK signaling pathway.

TL;DR: It is demonstrated that COL1A1-014 play an important regulatory role in GC development by functioning as a ceRNA in regulating the CXCL12/CXCR4 axis via sponging miR-1273h-5p.

TL;DR: KXS exerted antidepressant effects by regulating the signaling pathways involved in lipid metabolism disorders, and KXS treatment could reverse these changes in DPs and rats exposed to chronic and unpredictable mild stress.

TL;DR: Kai-Xin-San has an important role in regulating the key node proteins in the synaptic signaling network, and are helpful to better understand the mechanism of the antidepressive effects of Kai-XIn-San and to provide objective theoretical support for its clinical application.

TL;DR: Results indicated that MI comorbid with depression may damage the MMP balance in the central and peripheral system, and KXS may have a direct anti-depressive and cardio‑protective effect by regulating the level of MMPs and associated myocardial apoptosis.