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Xiangpei Zeng
Researcher at University of North Texas Health Science Center
Publications - 15
Citations - 528
Xiangpei Zeng is an academic researcher from University of North Texas Health Science Center. The author has contributed to research in topics: Massive parallel sequencing & Illumina dye sequencing. The author has an hindex of 11, co-authored 15 publications receiving 444 citations. Previous affiliations of Xiangpei Zeng include University of North Texas.
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Journal ArticleDOI
High-quality and high-throughput massively parallel sequencing of the human mitochondrial genome using the Illumina MiSeq.
Jonathan L. King,Bobby LaRue,Nicole M.M. Novroski,Monika Stoljarova,Seung Bum Seo,Xiangpei Zeng,David H. Warshauer,Carey Davis,Walther Parson,Antti Sajantila,Bruce Budowle +10 more
TL;DR: An overall increase in haplotype or genetic diversity and random match probability, as well as better haplogroup assignment demonstrates that MPS of the mtGenome using the Illumina MiSeq system is a viable and reliable methodology.
Journal ArticleDOI
High sensitivity multiplex short tandem repeat loci analyses with massively parallel sequencing.
Xiangpei Zeng,Jonathan L. King,Monika Stoljarova,David H. Warshauer,Bobby LaRue,Antti Sajantila,Antti Sajantila,Jaynish Patel,Douglas R. Storts,Bruce Budowle,Bruce Budowle +10 more
TL;DR: These studies indicate that this STR multiplex system and the Illumina MiSeq can generate reliable STR profiles at a sensitivity level that competes with current widely used CE-based method.
Journal ArticleDOI
Underlying Data for Sequencing the Mitochondrial Genome with the Massively Parallel Sequencing Platform Ion Torrent™ PGM™
Seung Bum Seo,Xiangpei Zeng,Jonathan L. King,Bobby LaRue,Mourad Assidi,Mohamed H Al-Qahtani,Antti Sajantila,Antti Sajantila,Bruce Budowle,Bruce Budowle +9 more
TL;DR: The results of this study supported that whole mtGenome sequence data with high accuracy can be obtained using the PGM platform and multiplexing of samples was demonstrated which can improve throughput and reduce cost per sample analyzed.
Journal ArticleDOI
An evaluation of the PowerSeq™ Auto System: A multiplex short tandem repeat marker kit compatible with massively parallel sequencing.
Xiangpei Zeng,Jonathan L. King,Spencer Hermanson,Jaynish Patel,Douglas R. Storts,Bruce Budowle +5 more
TL;DR: These studies indicate that the PowerSeq Auto System and the Illumina MiSeq can generate concordant results with current CE-based methods and MPS-based systems can facilitate mixture deconvolution with the detection of intra-repeat variations within length-based STR alleles.
Journal ArticleDOI
Increasing the discrimination power of ancestry- and identity-informative SNP loci within the ForenSeq™ DNA Signature Prep Kit
Jonathan L. King,Jennifer D. Churchill,Nicole M.M. Novroski,Xiangpei Zeng,David H. Warshauer,Lay Hong Seah,Bruce Budowle +6 more
TL;DR: The use of single nucleotide polymorphisms in forensic genetics has been limited to challenged samples with low template and/or degraded DNA, but the recent introduction of massively parallel sequencing technologies has expanded the potential applications of these markers and increased the discrimination power of well-established loci by considering variation in the flanking regions of target loci.