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Xiangxi Wang
Researcher at Chinese Academy of Sciences
Publications - 99
Citations - 8097
Xiangxi Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Antibody & Monoclonal antibody. The author has an hindex of 27, co-authored 76 publications receiving 3718 citations. Previous affiliations of Xiangxi Wang include Nankai University.
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Journal ArticleDOI
Development of an inactivated vaccine candidate for SARS-CoV-2.
Qiang Gao,Linlin Bao,Haiyan Mao,Lin Wang,Kangwei Xu,Minnan Yang,Li Yajing,Ling Zhu,Nan Wang,Zhe Lv,Hong Gao,Ge Xiaoqin,Biao Kan,Yaling Hu,Jiangning Liu,Fang Cai,Deyu Jiang,Yanhui Yin,Cheng-Feng Qin,Jing Li,Xuejie Gong,Xiuyu Lou,Wen Shi,Dongdong Wu,Hengming Zhang,Zhu Lang,Wei Deng,Li Yurong,Jinxing Lu,Changgui Li,Xiangxi Wang,Weidong Yin,Yanjun Zhang,Chuan Qin +33 more
TL;DR: Preclinical results of an early vaccine candidate called PiCoVacc, which protected rhesus macaque monkeys against SARS-CoV-2 infection when analyzed in short-term studies, support the clinical development and testing of Pi coVacc for use in humans.
Journal ArticleDOI
Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18-59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial.
Yanjun Zhang,Gang Zeng,Hongxing Pan,Changgui Li,Yaling Hu,Kai Chu,Weixiao Han,Zhen Chen,Rong Tang,Weidong Yin,Xin Chen,Yuansheng Hu,Xiao-Yong Liu,Cong-Bing Jiang,Jingxin Li,Minnan Yang,Yan Song,Xiangxi Wang,Qiang Gao,Fengcai Zhu +19 more
TL;DR: The primary safety endpoint was adverse reactions within 28 days after injection in all participants who were given at least one dose of study drug (safety population).
Journal ArticleDOI
BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection
Yunlong Cao,Ayijiang Yisimayi,F. Jian,Weiliang Song,T. Xiao,Lei Wang,Shuo Du,Qianqian Li,Xiao-song Chen,Yuanling Yu,Peng Wang,Zhiying Zhang,Pulan Liu,Ran An,Xiaohua Hao,Yao Wang,Jing Wang,Rui Feng,Haiyan Sun,Li-Jin Zhao,Wen Zhang,Dong Zhao,Jiang Zheng,Lingling Yu,Can Li,Na Zhang,Rui Wang,Xiaowei Niu,Siyuan Yang,Xuetao Song,Yangyang Chai,Ye Hu,Yansong Shi,Lin-Sheng Zheng,Zhiqiang Li,Qingqing Gu,Fei Shao,Weijin Huang,Ronghua Jin,Zhong-yang Shen,Youchun Wang,Xiangxi Wang,Junyu Xiao,Xiaoliang Sunney Xie +43 more
TL;DR: In this paper , the authors show that BA.4/BA.5 exhibit higher transmissibility than BA.2.1, BA.12.1 and BA.1.
Journal ArticleDOI
BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection
Yunlong Cao,Ayijiang Yisimayi,F. Jian,Weiliang Song,T. Xiao,Lei Wang,Shuo Du,Jing Wang,Qianqian Li,Xiao-song Chen,Yuanling Yu,Peng Wang,Zhiying Zhang,Pulan Liu,Ran An,Xiaohua Hao,Yao Wang,Rui Feng,Haiyan Sun,Li-Jin Zhao,Wen Zhang,Dong Zhao,Jiang Zheng,Ling-li Yu,Can Li,Na Zhang,Rui Wang,Xiaowei Niu,Siyuan Yang,Xuetao Song,Yangyang Chai,Yeping Hu,Yansong Shi,Lin-Sheng Zheng,Zhiqiang Li,Qingqing Gu,Fei Shao,Weijin Huang,Ronghua Jin,Zhong-yang Shen,Youchun Wang,Xiangxi Wang,Junyu Xiao,Xiaoliang Sunney Xie +43 more
TL;DR: In this article , the authors show that BA.4/BA.5 exhibit higher transmissibility than BA.2.1, BA.12.1 and BA.1.
Journal ArticleDOI
A single mutation in the prM protein of Zika virus contributes to fetal microcephaly
Ling Yuan,Xing Yao Huang,Zhong-Yu Liu,Feng Zhang,Xingliang Zhu,Jiu Yang Yu,Xue Ji,Yan Peng Xu,Guanghui Li,Cui Li,Hong Jiang Wang,Yong Qiang Deng,Menghua Wu,Meng Li Cheng,Qing Ye,Dong Yang Xie,Xiaofeng Li,Xiangxi Wang,Weifeng Shi,Baoyang Hu,Pei Yong Shi,Zhiheng Xu,Cheng-Feng Qin +22 more
TL;DR: A single serine-to-asparagine substitution in the viral polyprotein substantially increased ZIKV infectivity in both human and mouse neural progenitor cells (NPCs) and led to more severe microcephaly in the mouse fetus, as well as higher mortality rates in neonatal mice.