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Xianzhi Lin
Researcher at Cedars-Sinai Medical Center
Publications - 29
Citations - 1722
Xianzhi Lin is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: RNA & Kaposi's sarcoma-associated herpesvirus. The author has an hindex of 17, co-authored 29 publications receiving 1347 citations. Previous affiliations of Xianzhi Lin include University of California, Los Angeles & Chinese Academy of Sciences.
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Journal ArticleDOI
The Landscape of MicroRNA, Piwi-Interacting RNA, and Circular RNA in Human Saliva
Jae Hoon Bahn,Qing Zhang,Feng Li,Tak Ming Chan,Xianzhi Lin,Yong Kim,David T.W. Wong,Xinshu Xiao +7 more
TL;DR: This study provides a comprehensive landscape of ncRNA species in human saliva that will facilitate further biomarker discoveries and lay a foundation for future studies related to ncRNAs inhuman saliva.
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miR-K12-7-5p Encoded by Kaposi's Sarcoma-Associated Herpesvirus Stabilizes the Latent State by Targeting Viral ORF50/RTA
TL;DR: It is found that miR-K12-7 targeted the RTA 3′ untranslated region (RTA3′UTR) in a seed sequence-dependent manner and that this miRNA contributes to the maintenance of viral latency.
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Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways
TL;DR: The first global study of ADAR1-RNA interaction in human cells using CLIP-Seq is reported, revealing functional and biophysical targets of ADar1 in the regulation of alternative 3' UTR usage and miRNA biogenesis.
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A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKε.
TL;DR: This work reports that a viral miRNA, miR-K12-11, encoded by Kaposi's sarcoma-associated herpesvirus (KSHV) is critical for the modulation of IFN signaling and acts through targeting I-kappa-B kinase epsilon (IKKɛ).
Journal ArticleDOI
RNA editing in nascent RNA affects pre-mRNA splicing.
Yun-Hua Esther Hsiao,Jae Hoon Bahn,Yun Yang,Xianzhi Lin,Stephen Tran,Ei-Wen Yang,Giovanni Quinones-Valdez,Xinshu Xiao +7 more
TL;DR: A second class of exons whose splicing is likely modulated by RNA secondary structures that are recognized by the RNA editing machinery is identified and the repertoire of functional RNA editing sites is expanded.